Systemic Inflammation in Hip Fracture and Osteoarthritis: Insights into Pathways of Immunoporosis [PDF]
International Journal of Molecular SciencesInflammaging has been implicated in age-related bone loss and fragility fractures through immune-mediated effects on bone turnover. We aimed to explore the relationship between systemic inflammatory markers and bone health in older adults, focusing on ...
Nicolas Martínez-Velilla +2 more
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Immunoporosis: The hidden link between aging immune cells and bone fragility [PDF]
Journal of Orthopaedic TranslationOsteoporosis (OP) is a serious public health problem affecting the elderly worldwide. The immune system is well-known to play an important role in bone metabolism and formation. However, immunosenescence, defined as the gradual deterioration of immune system function with aging, has become one of the key factors that drive OP, referred to as ...
Chao Wan, Qin Shi, Huilin Yang
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Osteoimmunology: an interdisciplinary approach to studying the relationships between immune and bone cells [PDF]
Медицинская иммунология, 2022 In this review, we discuss molecular and cellular mechanisms underlying cross-talk between immune cells and bone cells, both in healthy conditions and in some diseases.
V. S. Shirinsky, I. V. Shirinsky
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Immunoporosis: A New Role for Invariant Natural Killer T (NKT) Cells Through Overexpression of Nuclear Factor-κB Ligand (RANKL) [PDF]
Medical Science Monitor, 2019 BACKGROUND Osteoporosis affects millions of postmenopausal women worldwide. Invariant natural killer T cells (iNKT) are important cells for bone homeostasis. The sim of this study was to investigate the contribution of invariant natural killer T cells (iNKT) in the increased receptor activator of the nuclear factor-kappaB ligand (RANKL) pool and bone ...
Ioannis Kotsianidis +2 more
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The Rising Era of “Immunoporosis”: Role of Immune System in the Pathophysiology of Osteoporosis
Journal of Inflammation Research, 2022 Rupesh K Srivastava, Leena Sapra Immunoporosis Lab, Department of Biotechnology, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, IndiaCorrespondence: Rupesh K Srivastava, Tel +91 11-26593548, Email rupesh_srivastava13@yahoo.co.in ...
Srivastava RK, Sapra L
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Editorial: Recent Advances in Basic and Translational Osteoimmunology [PDF]
Frontiers in Immunology, 2021 Rupesh K. Srivastava +4 more
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Editorial: Gut microbiota and gut-associated metabolites in bone health [PDF]
Frontiers in Endocrinology, 2023 Rupesh K. Srivastava +2 more
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The Rising Era of "Immunoporosis": Role of Immune System in the Pathophysiology of Osteoporosis. [PDF]
J Inflamm Res, 2022 Discoveries in the last few years have emphasized the existence of an enormous breadth of communication between bone and the immune system in maintaining skeletal homeostasis. Originally, the discovery of various factors was assigned to the immune system viz. interleukin (IL)-6, IL-10, IL-17, tumor necrosis factor (TNF)-α, receptor activator of nuclear
Srivastava RK, Sapra L.
europepmc +4 more sources
COVID-19 induced ARDS: immunopathology and therapeutics
Exploration of Immunology, 2023 The coronavirus disease-2019 (COVID-19) pandemic is a significant threat in the modern era. Clinical studies show that the most common symptom of severe COVID-19 is viral pneumonia-induced acute respiratory distress syndrome (ARDS).
Sneha Das +3 more
doaj +1 more source