Results 1 to 10 of about 2,318 (174)

Current Understanding of Osteoimmunology in Certain Osteoimmune Diseases

Frontiers in Cell and Developmental Biology, 2021
The skeletal system and immune system seem to be two independent systems. However, there in fact are extensive and multiple crosstalk between them. The concept of osteoimmunology was created to describe those interdisciplinary events, but it has been ...
Yufei Tang, Hui Yu, Bingfeng Wu
exaly   +3 more sources

Unraveling the mechanisms of bone diseases: targeting dendritic cells in osteoimmunology for internal homeostasis balance [PDF]

Bone Research
Bone repair and regeneration is a complex spatiotemporal process recruiting a variety of cell types, which need to precisely mediated for effective healing post-damage.
Yanqi Chen, Siyuan Wang, Xiaoyu Chen, Zhifang Wu, Fuming He, Qianming Chen   +5 more
doaj   +2 more sources

Osteoimmunology: An Overview of the Interplay of the Immune System and the Bone Tissue in Fracture Healing

Surgeries
Bone healing occurs through three consecutive and interdependent phases. While the acute inflammatory response is vital to fracture healing, chronic and systemic inflammation negatively affect the healing process.
Rahul Gawri, Prism Schneider, Derek H Rosenzweig   +2 more
exaly   +3 more sources

Sensory Nerve‐Derived CGRP Controls Osteoclastogenesis by Limiting Macrophage Bioenergetics in Bone Repair [PDF]

Advanced Science
Bone healing is a tightly orchestrated, multiphase process that requires coordinated interactions between immune cells and skeletal cells. Sensory nerves act as intrinsic effectors of the inflammatory response, whose role in osteoimmunology during ...
Jiaying Liu, Ting Zhang, Yuqing Mu, Lili Li, Ju Jin, Kevin J Dudley, Wendong Gao, Donglin Cai, Fuhua Yan, Lan Xiao, Yin Xiao   +10 more
doaj   +2 more sources

COVID-19 induced ARDS: immunopathology and therapeutics

Exploration of Immunology, 2023
The coronavirus disease-2019 (COVID-19) pandemic is a significant threat in the modern era. Clinical studies show that the most common symptom of severe COVID-19 is viral pneumonia-induced acute respiratory distress syndrome (ARDS).
Sneha Das, Tamanna Sharma, Asha Bhardwaj, Rupesh K. Srivastava   +3 more
doaj   +1 more source

T Cell Protein Tyrosine Phosphatase in Osteoimmunology

Frontiers in Immunology, 2021
Osteoimmunology highlights the two-way communication between bone and immune cells. T cell protein tyrosine phosphatase (TCPTP), also known as protein-tyrosine phosphatase non-receptor 2 (PTPN2), is an intracellular protein tyrosine phosphatase (PTP ...
Ya-nan Wang, Ya-nan Wang, Ya-nan Wang, Shiyue Liu, Shiyue Liu, Shiyue Liu, Tingting Jia, Tingting Jia, Tingting Jia, Yao Feng, Yao Feng, Yao Feng, Wenjing Zhang, Wenjing Zhang, Wenjing Zhang, Xin Xu, Xin Xu, Xin Xu, Dongjiao Zhang, Dongjiao Zhang, Dongjiao Zhang   +20 more
doaj   +1 more source

Decreased Survival of Invasive Ductal Breast Cancer Patients With Two Macrometastatic Lymph Nodes Among Few Resected Ones: Should Current Sentinel-Lymph-Node Guidelines Be Revised?

Frontiers in Oncology, 2021
PurposeSentinel-lymph-node (SLN) biopsy (SLB) is an efficient and safe axillary surgical approach with decreased morbidity than total axillary lymph node dissection (ALND) in initial patients (T1–T2).
Felipe A. C. Luz, Felipe A. C. Luz, Rogério A. Araújo, Rogério A. Araújo, Marcelo J. B. Silva   +4 more
doaj   +1 more source

Leveraging mice with diverse microbial exposures for advances in osteoimmunology

Frontiers in Endocrinology, 2023
The skeletal and immune systems are intricately intertwined within the bone marrow microenvironment, a field of study termed osteoimmunology. Osteoimmune interactions are key players in bone homeostasis and remodeling.
Sarah E. Little-Letsinger, Sara E. Hamilton   +1 more
doaj   +1 more source

Osteometabolism: Metabolic Alterations in Bone Pathologies

Cells, 2022
Renewing interest in the study of intermediate metabolism and cellular bioenergetics is brought on by the global increase in the prevalence of metabolic illnesses.
Rupesh K. Srivastava, Leena Sapra, Pradyumna K. Mishra   +2 more
doaj   +1 more source

Bifidobacterium longum Ameliorates Ovariectomy-Induced Bone Loss via Enhancing Anti-Osteoclastogenic and Immunomodulatory Potential of Regulatory B Cells (Bregs)

Frontiers in Immunology, 2022
Discoveries in the last few years have emphasized the existence of an enormous breadth of communication between osteo-immune systems. These discoveries fuel novel approaches for the treatment of several bone pathologies including osteoporosis ...
Leena Sapra, Niti Shokeen, Konica Porwal, Chaman Saini, Asha Bhardwaj, Mary Mathew, Pradyumna K. Mishra, Naibedya Chattopadhyay, Hamid Y. Dar, Hamid Y. Dar, Bhupendra Verma, Rupesh K. Srivastava   +11 more
doaj   +1 more source