Results 21 to 30 of about 2,318 (174)

Osteoimmunomodulatory Nanoparticles for Bone Regeneration

open access: yesNanomaterials, 2023
Treatment of large bone fractures remains a challenge for orthopedists. Bone regeneration is a complex process that includes skeletal cells such as osteoblasts, osteoclasts, and immune cells to regulate bone formation and resorption.
Jingyi Wen   +8 more
doaj   +1 more source

Interferon-Gamma-Mediated Osteoimmunology

open access: yesFrontiers in Immunology, 2018
Osteoimmunology is the interdiscipline that focuses on the relationship between the skeletal and immune systems. They are interconnected by shared signal pathways and cytokines.
Mengjia Tang   +3 more
doaj   +1 more source

Role of Hippo-YAP Signaling in Osseointegration by Regulating Osteogenesis, Angiogenesis, and Osteoimmunology

open access: yesFrontiers in Cell and Developmental Biology, 2020
The social demand for dental implantation is growing at a rapid rate, while dentists are faced with the dilemma of implantation failures associated with unfavorable osseointegration. Clinical-friendly osteogenesis, angiogenesis and osteoimmunology around
Anqi Zhou   +8 more
doaj   +1 more source

Osteoclastogenesis and osteoimmunology

open access: yesFrontiers in Bioscience, 2014
Bone is continuously renewed through a dynamic balance between bone resorption and formation and is the fundamental basis for maintaining normal bone mass and architecture by osteoclasts (bone resorption) and osteoblasts (bone formation). Bone resorption is an elementary cellular activity in the modeling of the skeleton during growth and development ...
Wei, Feng   +3 more
openaire   +2 more sources

The emerging field of osteoimmunology [PDF]

open access: yesImmunologic Research, 2009
Recent studies have elucidated unanticipated connections between the immune and skeletal systems, and this relationship has led to the development of a new field known as osteoimmunology. The goal of research in this field is to: (1) further understand how the bone microenvironment influences immune cell ontogeny and subsequent effector functions, and (
Kofi A, Mensah   +2 more
openaire   +2 more sources

Cell-adhesion molecules and their soluble forms: Promising predictors of “tumor progression” and relapse in leukemia

open access: yesTumor Biology, 2018
Some surface markers are used to discriminate certain leukemic subpopulations that retain a greater oncogenic potential than others, and, for this reason, they were termed as leukemic stem cells, similar to the concept of cancer stem cells in carcinoma ...
Ieda Cristina Cunha Ferreira e Fonseca   +3 more
doaj   +1 more source

Foxp3+ Regulatory T Cells in Bone and Hematopoietic Homeostasis

open access: yesFrontiers in Endocrinology, 2019
The bone represents surprisingly dynamic structures that are subject to constant remodeling by the concerted action of bone-forming osteoblasts and bone-resorbing osteoclasts - two cell subsets of distinct developmental origin that are key in maintaining
Luise Fischer   +8 more
doaj   +1 more source

Cytokine-Mediated Bone Destruction in Rheumatoid Arthritis

open access: yesJournal of Immunology Research, 2014
Bone homeostasis, which involves formation and resorption, is an important process for maintaining adequate bone mass in humans. Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation and bone loss, leading to joint destruction ...
Seung Min Jung   +4 more
doaj   +1 more source

Osteoimmunology: A Brief Introduction [PDF]

open access: yesImmune Network, 2013
Recent investigations have demonstrated extensive reciprocal interactions between the immune and skeletal systems, resulting in the establishment of osteoimmunology as a cross-disciplinary field. Here we highlight core concepts and recent advances in this emerging area of study.
Greenblatt, Matthew B., Shim, Jae-Hyuck
openaire   +2 more sources

The Effect of Calendula officinalis on Oxidative Stress and Bone Loss in Experimental Periodontitis

open access: yesFrontiers in Physiology, 2017
Periodontitis is associated with reduced antioxidant capacity and increased oxidative damage. Oxidative stress induces inflammation and bone loss contributing to the pathological progression of periodontal disease.
Mariana dos Reis Lima   +5 more
doaj   +1 more source

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