Results 31 to 40 of about 2,318 (174)
Osteoimmunology: The Regulatory Roles of T Lymphocytes in Osteoporosis
Frontiers in Endocrinology, 2020 Immune imbalance caused bone loss. Osteoimmunology is emerging as a new interdisciplinary field to explore the shared molecules and interactions between the skeletal and immune systems.
Wenjuan Zhang +3 more
doaj +1 more source
Frontiers in Immunology, 2022 Despite significant increases in human lifespan over the last century, adoption of high calorie diets (HCD) has driven global increases in type-2 diabetes, obesity and cardiovascular disease, disorders precluding corresponding improvements in healthspan.
Margaret M. Harnett +10 more
doaj +1 more source
Optimizing Delivery of Therapeutic Growth Factors for Bone and Cartilage Regeneration
Gels, 2023 Bone- and cartilage-related diseases, such as osteoporosis and osteoarthritis, affect millions of people worldwide, impairing their quality of life and increasing mortality.
Eri Takematsu +6 more
doaj +1 more source
Applied Sciences, 2021 (1) Background: Intrinsic characteristics of the implant surface and the possible presence of endotoxins may affect the bone–implant interface and cause an inflammatory response.
Maria Menini +5 more
doaj +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
eLife, 2020 Bone destruction relies on interactions between bone and immune cells. Bone-resorbing osteoclasts (OCLs) were recently identified as innate immune cells activating T cells toward tolerance or inflammation.
Maria-Bernadette Madel +11 more
doaj +1 more source
Bone Grafts: Everything You Need to Know
Journal of Periodontal Research, EarlyView.This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen +5 more
wiley +1 more source
Myeloid A20 Regulates Periodontal Tissue Integrity and Temporomandibular Joint Structure
Journal of Periodontal Research, EarlyView.Dysregulation of A20 signaling has been implicated in several immune‐mediated diseases, including rheumatoid arthritis and psoriasis, conditions characterized by excessive NF‐κB activation and inflammatory tissue damage. The structural alterations observed in this model suggest that impaired regulation of innate immune signaling may increase ...
Karol Alí Apaza Alccayhuaman +6 more
wiley +1 more source
Osteoimmunology: memorandum for rheumatologists [PDF]
Science China Life Sciences, 2016 Rapid progress has been made in exploring the connections between the skeletal system and the immune system over the past decade. Bone tissue forms developmental niches for hematopoietic stem cells, and activated immune cells are involved in bone metabolism regulation and are potent mediators of osteoporosis and bone erosion under pathological ...
Zhao, Lidan, Huang, Linfang, Zhang, Xuan
openaire +2 more sources
Roles of Zinc Signaling in the Immune System
Journal of Immunology Research, 2016 Zinc (Zn) is an essential micronutrient for basic cell activities such as cell growth, differentiation, and survival. Zn deficiency depresses both innate and adaptive immune responses.
Shintaro Hojyo, Toshiyuki Fukada
doaj +1 more source