Results 1 to 10 of about 111,477 (307)
Tregs in transplantation tolerance: role and therapeutic potential [PDF]
Frontiers in Transplantation, 2023 CD4+ Foxp3+ regulatory T cells (Tregs) are indispensable for preventing autoimmunity, and they play a role in cancer and transplantation settings by restraining immune responses.
Alexandra Cassano +2 more
exaly +2 more sources
Homeostasis and function of regulatory T cells (Tregs) in vivo: lessons from TCR‐transgenic Tregs [PDF]
Immunological Reviews, 2014 The identification of CD25 and subsequently Forkhead box protein 3 (Foxp3) as markers for regulatory T cells (Tregs) has revolutionized our ability to explore this population experimentally.
Kesley Attridge, Lucy S K Walker
exaly +2 more sources
Antigen Specificity Enhances Disease Control by Tregs in Vitiligo [PDF]
Frontiers in Immunology, 2020 Vitiligo is an autoimmune skin disease characterized by melanocyte destruction. Regulatory T cells (Tregs) are greatly reduced in vitiligo skin, and replenishing peripheral skin Tregs can provide protection against depigmentation. Ganglioside D3 (GD3) is
Zhussipbek Mukhatayev +2 more
exaly +2 more sources
The Four types of Tregs in malignant lymphomas
Journal of Hematology & Oncology, 2011 Regulatory T cells (Tregs) are a specialized subpopulation of CD4+ T cells, which act to suppress the activation of other immune cells. Tregs represent important modulators for the interaction between lymphomas and host microenvironment.
Wang Jing, Ke Xiao-Yan
doaj +3 more sources
Immunometabolism of Tregs: mechanisms, adaptability, and therapeutic implications in diseases [PDF]
Frontiers in ImmunologyImmunometabolism is an emerging field that explores the intricate interplay between immune cells and metabolism. Regulatory T cells (Tregs), which maintain immune homeostasis in immunometabolism, play crucial regulatory roles.
Tiantian Ruan, Dengfu Yao, Min Yao
exaly +2 more sources
Cancer Biology & Medicine, 2021 Objective: Promotion of the proliferative expansion of CD4+Foxp3+ regulatory T cells (Tregs) is one of the side effects that limits the use of bleomycin (BLM) in the treatment of tumors. In this study, we examined the hypothesis that cyclophosphamide (CY)
Ping Li +6 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Mycobacterium tuberculosis (M. tb) gene Rv1515c encodes a conserved hypothetical protein exclusively present within organisms of MTB complex and absent in non-pathogenic mycobacteria.
Anshu Rani +10 more
doaj +1 more source
Indian Journal of Pathology and Microbiology, 2021 Context: Tumor immune microenvironment (TIME) is heterogeneous and dynamic. It exerts bimodal pro and antitumor effects. Among the TIME contributors, TAMs and Tregs are condemned as cancer cells allies rather than enemies; however, such contribution is ...
Lobna S Shash +2 more
doaj +1 more source
CD24+ MDSC-DCs Induced by CCL5-Deficiency Showed Improved Antitumor Activity as Tumor Vaccines
Global Medical Genetics, 2022 Background Dendritic cell (DC) tumor vaccine has been extensively utilized in preclinical and clinical studies; however, this technique has encountered many difficulties, particularly in late-stage tumor patients.
Lei Huang, Zequn Ding, Yan Zhang
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HMGB1 Signaling-Mediated Tumor Immunity in Cancer Progress
Frontiers in Bioscience-Landmark, 2023 Tumor immunity is a cycle that begins with the release of antigens from tumor cells and ends with the destruction of tumor cells. High mobility group box 1 (HMGB1) is a nonhistone protein widely present in the nucleus of mammalian cells and can be ...
Jinlin Wen, Xinyan Zhang
doaj +1 more source