Results 11 to 20 of about 111,477 (307)
ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases [PDF]
Frontiers in Immunology, 2020 Recent studies have reported the pathological effect of ICOS+ T cells, but ICOS signals also widely participate in anti-inflammatory responses, particularly ICOS+ regulatory T (Treg) cells.
Dan-Yang Li +3 more
doaj +3 more sources
Current Rheumatology Reports, 2018 Purpose of review: There has been great interest in understanding why T regulatory cells (Tregs) are reduced in number and/or in function in several autoimmune diseases including systemic lupus erythematosus (SLE).
Antonio La Cava, La Cava, Antonio
core +5 more sources
Once a Treg, always a Treg? [PDF]
Immunological Reviews, 2014 SummaryRegulatory T cells (Tregs) prevail as a specialized cell lineage that has a central role in the dominant control of immunological tolerance and maintenance of immune homeostasis. Thymus‐derived Tregs (tTregs) and their peripherally induced counterparts (pTregs) are imprinted with unique Forkhead box protein 3 (Foxp3)‐dependent and independent ...
Deepali V, Sawant, Dario A A, Vignali
openaire +2 more sources
Annual Review of Immunology, 2016 The immune system is responsible for defending an organism against the myriad of microbial invaders it constantly confronts. It has become increasingly clear that the immune system has a second major function: the maintenance of organismal homeostasis. Foxp3+CD4+regulatory T cells (Tregs) are important contributors to both of these critical activities,
Marisella, Panduro +2 more
openaire +2 more sources
Mechanistic Insight into PPARγ and Tregs in Atherosclerotic Immune Inflammation
Frontiers in Pharmacology, 2021 Atherosclerosis (AS) is the main pathological cause of acute cardiovascular and cerebrovascular diseases, such as acute myocardial infarction and cerebral apoplexy.
Zhao Gao +14 more
doaj +1 more source
Frontiers in Immunology, 2020 Uterine receptivity and embryo implantation are two main processes that need a finely regulated balance between pro-inflammatory and tolerogenic mediators to allow a successful pregnancy.
Lucila Gallino +11 more
doaj +1 more source
Toxins, 2020 Bee venom phospholipase A2 is a lipolytic enzyme in bee venom that catalyzes hydrolysis of the sn-2 ester bond of membrane phospholipids to produce free fatty acid and lysophospholipids.
Hyunjung Baek +6 more
doaj +1 more source
Frontiers in Aging, 2021 Respiratory infection caused by Streptococcus pneumoniae is a leading cause of morbidity and mortality in older adults. Acquired CD4+ T cell mechanism are essential for the protection against colonization and subsequent development of infections by S ...
Samantha W. J. He +7 more
doaj +1 more source
An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment [PDF]
, 2017 Regulatory T cells (Tregs) play a pivotal role in maintaining immunological tolerance, but they can also play a detrimental role by preventing antitumor responses.
Jassem, W. +17 more
core +1 more source