Results 11 to 20 of about 120,068 (304)
ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases [PDF]
Frontiers in Immunology, 2020 Recent studies have reported the pathological effect of ICOS+ T cells, but ICOS signals also widely participate in anti-inflammatory responses, particularly ICOS+ regulatory T (Treg) cells.
Dan-Yang Li +3 more
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The Four types of Tregs in malignant lymphomas [PDF]
Journal of Hematology & Oncology, 2011 Regulatory T cells (Tregs) are a specialized subpopulation of CD4+ T cells, which act to suppress the activation of other immune cells. Tregs represent important modulators for the interaction between lymphomas and host microenvironment.
Wang Jing, Ke Xiao-Yan
doaj +3 more sources
Current Rheumatology Reports, 2018 There has been great interest in understanding why T regulatory cells (Tregs) are reduced in number and/or in function in several autoimmune diseases including systemic lupus erythematosus (SLE). Although research has provided some answers, there is still much to learn.Recent investigations on the mechanisms responsible for the impairment of the Tregs ...
Antonio La Cava, La Cava, Antonio
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Once a Treg, always a Treg? [PDF]
Immunological Reviews, 2014 SummaryRegulatory T cells (Tregs) prevail as a specialized cell lineage that has a central role in the dominant control of immunological tolerance and maintenance of immune homeostasis. Thymus‐derived Tregs (tTregs) and their peripherally induced counterparts (pTregs) are imprinted with unique Forkhead box protein 3 (Foxp3)‐dependent and independent ...
Deepali V, Sawant, Dario A A, Vignali
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Annual Review of Immunology, 2016 The immune system is responsible for defending an organism against the myriad of microbial invaders it constantly confronts. It has become increasingly clear that the immune system has a second major function: the maintenance of organismal homeostasis. Foxp3+CD4+regulatory T cells (Tregs) are important contributors to both of these critical activities,
Marisella, Panduro +2 more
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Tregs and allergic disease [PDF]
Journal of Clinical Investigation, 2004 Allergic diseases such as asthma, rhinitis, and eczema are increasing in prevalence and affect up to 15% of populations in Westernized countries. The description of Tregs as T cells that prevent development of autoimmune disease led to considerable interest in whether these Tregs were also normally involved in prevention of sensitization to allergens ...
Douglas S, Robinson +2 more
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Frontiers in Cell and Developmental Biology, 2021 Sickle Cell Disease (SCD) is an autosomal recessive disorder resulting from a β-globin gene missense mutation and is among the most prevalent severe monogenic disorders worldwide.
Alba Saenz de Villaverde Cortabarria +6 more
doaj +1 more source
Frontiers in Microbiology, 2022 ObjectiveThis study aims to explore how gut microbiota dysbiosis affects allergic rhinitis (AR) and whether short-chain fatty acids (SCFAs) play a role in this process.MethodsA mouse gut microbiota dysbiosis model was established by adding vancomycin to ...
Zhen Chen +15 more
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An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment [PDF]
, 2017 Regulatory T cells (Tregs) play a pivotal role in maintaining immunological tolerance, but they can also play a detrimental role by preventing antitumor responses.
Jassem, W. +17 more
core +1 more source