Results 41 to 50 of about 124,395 (259)
Cancer Biology & Medicine, 2021 Objective: L1 cell adhesion molecule (L1CAM) exhibits oncogenic activity in tumors. However, the link between L1CAM and the tumor microenvironment remains poorly understood in patients with esophageal squamous cell carcinoma (ESCC).
Xuan Zhao +12 more
doaj +1 more source
Ncf1−/− Tregs were hypofunctional than WT Tregs.
, 2014 (A) A representative panel of FACS plots for the analysis of suppressive function of Tregs from Ncf1−/− mice. On the 3rd day of culture, live CD4+ cells were gated for analysis.
Anbok Lee (532405) +8 more
core +1 more source
Tumor inflating lymphocytes. Purification, expanding and cytotoxicity analisys on primary tumor cultures [PDF]
Клиническая практика, 2020 Background. Tumor Infiltrating Lymphocytes (TILs) is one of the most promising sources of autologous cytotoxic T-cells for adoptive immunotherapy, which has already shown high efficiency in the treatment of metastatic melanoma.
G. M. Yusubalieva +13 more
doaj +1 more source
Tregs levels and phenotype modifications during Amyotrophic Lateral Sclerosis course [PDF]
Introduction: T regulatory cells (Tregs) inversely correlate with disease progression in Amyotrophic Lateral Sclerosis (ALS) and fast-progressing ALS patients have been reported to exhibit dysfunctional, as well as reduced, levels of Tregs.
Martinelli, Ilaria +20 more
core +3 more sources
Epigenetics, 2018 IL2RA, a subunit of the high affinity receptor for interleukin-2 (IL2), plays a crucial role in immune homeostasis. Notably, IL2RA expression is induced in CD4+ T cells in response to various stimuli and is constitutive in regulatory T cells (Tregs).
Marie-Pierre Belot +3 more
doaj +1 more source
GPx1−/− Tregs were hyperfunctional than WT Tregs.
, 2014 (A) A representative panel of FACS plots for the analysis of suppressive function of Tregs from GPx1−/− mice. On the 3rd day of culture, live CD4+ cells were gated for analysis.
Anbok Lee (532405) +8 more
core +1 more source
The frequency of Tregs, the frequency of Th17 cells, and Tregs/Th17 ratio are correlated with RAI.
, 2014 To confirm whether Tregs, Th17 cells and Tregs/Th17 were associated with the liver allograft rejection, we analyzed the correlation between RAI and the frequency of circulating Tregs, the frequency of circulating Th17 cells, and Tregs/Th17 ratio.
Fu-Sheng Wang (300650) +9 more
core +1 more source
Kinase signaling network specificities of human Tregs.
, 2012 Comparative kinome analysis revealed differential kinase expression in Tregs and Teffs. Altered kinase expression in Tregs (RF = Treg/Teff) is indicated by green (increased expression in Tregs) and red boxes (reduced expression in Tregs).
Tobias Reinl (150919) +6 more
core +1 more source
, 2021 Dysregulations in the differentiation of CD4+-regulatory-T-cells (Tregs) and CD4+-responder-T-cells (Tresps) are involved in the development of active systemic lupus erythematosus (SLE).
Florian Kälble +5 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source