Results 31 to 40 of about 120,068 (304)

FoxP3+ Tregs infiltration meta-analysis.

, 2023
Influence of NAC in the FoxP3+ Tregs infiltration of BC tumors. Forest plot for the different outcomes regarding FoxP3+ Tregs infiltration before and after NAC.
María Alejandra Villota-Álava (15368651), Nicolás Lalinde-Ruíz (15368648), Ivon Johanna Rodríguez-Rodríguez (15368654), Laura Camila Martínez-Enriquez (15368639), Carlos Alberto Parra-López (14599806), Esteban Alejandro Velandia-Vargas (15368645), María del Pilar Montilla-Velásquez (15368657), Manuela Llano-León (14599800), Oscar Mauricio Rodríguez-Bohórquez (15368642)   +8 more
core   +1 more source

The essential schistosome tegumental ectoenzyme SmNPP5 can block NAD-induced T cell apoptosis

Virulence, 2020
Infection with intravascular platyhelminths of the genus Schistosoma can result in the debilitating disease schistosomiasis. Schistosomes (blood flukes) can survive in the host for many years.
Catherine S. Nation, Akram A. Da’Dara, Patrick J. Skelly   +2 more
doaj   +1 more source

RETRACTED: Tregs depletion aggravates activation of astrocytes by modulating IL-10/GXP4 following cerebral infarction

Frontiers in Immunology, 2023
BackgroundTregs plays a critical role in the development of secondary injuries in diseases. Accumulating evidence suggests an association between ischemic stroke and renal dysfunction; however, the underlying mechanisms remain unclear.
Shuai Wang, Yubin Shi, Yanqi Zhang, Fengyun Yuan, Mintao Mao, Jun Ma   +5 more
doaj   +1 more source

Tregs

, 2015
Regulatory T cell subsets.
Johan Carlsson (826313)
core   +1 more source

Breast Cancer Cells and PD-1/PD-L1 Blockade Upregulate the Expression of PD-1, CTLA-4, TIM-3 and LAG-3 Immune Checkpoints in CD4⁺ T Cells

Vaccines, 2019
Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype, and it exhibits resistance to common breast cancer therapies. Immune checkpoint inhibitors (ICIs) targeting programmed cell death 1 (PD-1) and its ligand, PD-L1, have been
Reem Saleh, Salman M Toor, Sarah Khalaf, Eyad Elkord   +3 more
doaj   +1 more source

Tivozanib mediated inhibition of c-Kit/SCF signaling on Tregs and MDSCs and reversal of tumor induced immune suppression correlates with survival of HCC patients

OncoImmunology, 2020
The immune modulatory effect of tivozanib, a tyrosine kinase inhibitor, and the underlying immune mechanisms impacting survival of HCC patients have not been investigated.
Suresh Gopi Kalathil, Katy Wang, Alan Hutson, Renuka Iyer, Yasmin Thanavala   +4 more
doaj   +1 more source

L1CAM overexpression promotes tumor progression through recruitment of regulatory T cells in esophageal carcinoma

Cancer Biology & Medicine, 2021
Objective: L1 cell adhesion molecule (L1CAM) exhibits oncogenic activity in tumors. However, the link between L1CAM and the tumor microenvironment remains poorly understood in patients with esophageal squamous cell carcinoma (ESCC).
Xuan Zhao, Shasha Liu, Xinfeng Chen, Jianyi Zhao, Feng Li, Qitai Zhao, Tan Xie, Lan Huang, Zhen Zhang, Yu Qi, Yang Yang, Song Zhao, Yi Zhang   +12 more
doaj   +1 more source

GPx1^−/− Tregs were hyperfunctional than WT Tregs.

, 2014
(A) A representative panel of FACS plots for the analysis of suppressive function of Tregs from GPx1−/− mice. On the 3rd day of culture, live CD4+ cells were gated for analysis.
Anbok Lee (532405), Jeong-Hae Kie (532407), Woosung Lim (532408), Byung-In Moon (532410), Ju-Young Seoh (439510), Eun-Jeong Choi (389699), Min-Pyo Hong (532406), Hyung-Ran Kim (532404), Hyeon Kook Lee (532409)   +8 more
core   +1 more source

Tumor inflating lymphocytes. Purification, expanding and cytotoxicity analisys on primary tumor cultures [PDF]

Клиническая практика, 2020
Background. Tumor Infiltrating Lymphocytes (TILs) is one of the most promising sources of autologous cytotoxic T-cells for adoptive immunotherapy, which has already shown high efficiency in the treatment of metastatic melanoma.
G. M. Yusubalieva, S. V. Petrichuk, A. L. Krivoshapkin, A. G. Kedrova, Yu. V. Ivanov, A. G. Vinokurov, A. A. Kalinkin, A. E. Sandjarov, S. V. Kim, A. V. Ponomarev, D. G. Kuptsova, Roman Ischenko, Alexander Troitskiy, V. P. Baklaushev   +13 more
doaj   +1 more source

GP96: safeguarding Treg

Oncotarget, 2015
FOXP3 positive regulatory T cells (Tregs) are key players in maintaining peripheral immune tolerance. Multiple molecules and signaling pathways are involved in regulating Treg function. Understanding these mechanisms is vital to designing Treg-targeted immunotherapeutic strategies for cancer and other diseases. A recent study uncovered that endoplasmic
Yongliang, Zhang, Ephraim, Ansa-Addo, Zihai, Li   +2 more
openaire   +2 more sources