Results 31 to 40 of about 111,477 (307)

MALAT1 Induces Food Allergy by Promoting Release of IL-6 from Dendritic Cells and Suppressing the Immunomodulatory Function of Tregs

Journal of Asthma and Allergy, 2022
Hua Feng,1,2 Xiujuan Xiong,3 Zhuo Chen,1 Nan Luo,2 Yongning Wu1,4,5 1State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, 330000, People’s Republic of China; 2School of Public Health, Nanchang University, Nanchang, 330006 ...
Feng H, Xiong X, Chen Z, Luo N, Wu Y
doaj  

Targeting crosstalk of STAT3 between tumor-associated M2 macrophages and Tregs in colorectal cancer

Cancer Biology & Therapy, 2023
A comprehensive analysis of the molecular mechanism underlying colorectal tumor evaluated the development of colorectal cancer (CRC) and proposed targeting small molecular inhibitors.
Lili Huang, Yu Zhao, Mengying Shan, Sitong Wang, Jianhua Chen, Zhuqing Liu, Qing Xu   +6 more
doaj   +1 more source

Increased Plasticity of FOXP3+ Treg under Pathological Conditions Convert Treg into Either Novel Treg or Th1‐Treg

The FASEB Journal, 2018
Naïve CD4+ Th (T helper cells) can differentiate/be polarized in to 9 terminally differentiated Th cell subsets depending on the cytokine repertoire and anatomical location. CD4+ FOXP3+ (forkhead box P3) regulatory T cells (Treg) are one of the Th subsets.
Keman Xu, William Y. Yang, Gayani K. Nanayakkara, Ying Shao, Fan Yang, Wenhui Hu, Eric T. Choi, Hong Wang, Xiaofeng Yang   +8 more
openaire   +1 more source

FoxP3+ Tregs infiltration meta-analysis.

, 2023
Influence of NAC in the FoxP3+ Tregs infiltration of BC tumors. Forest plot for the different outcomes regarding FoxP3+ Tregs infiltration before and after NAC.
María Alejandra Villota-Álava (15368651), Nicolás Lalinde-Ruíz (15368648), Ivon Johanna Rodríguez-Rodríguez (15368654), Laura Camila Martínez-Enriquez (15368639), Carlos Alberto Parra-López (14599806), Esteban Alejandro Velandia-Vargas (15368645), María del Pilar Montilla-Velásquez (15368657), Manuela Llano-León (14599800), Oscar Mauricio Rodríguez-Bohórquez (15368642)   +8 more
core   +1 more source

The essential schistosome tegumental ectoenzyme SmNPP5 can block NAD-induced T cell apoptosis

Virulence, 2020
Infection with intravascular platyhelminths of the genus Schistosoma can result in the debilitating disease schistosomiasis. Schistosomes (blood flukes) can survive in the host for many years.
Catherine S. Nation, Akram A. Da’Dara, Patrick J. Skelly   +2 more
doaj   +1 more source

RETRACTED: Tregs depletion aggravates activation of astrocytes by modulating IL-10/GXP4 following cerebral infarction

Frontiers in Immunology, 2023
BackgroundTregs plays a critical role in the development of secondary injuries in diseases. Accumulating evidence suggests an association between ischemic stroke and renal dysfunction; however, the underlying mechanisms remain unclear.
Shuai Wang, Yubin Shi, Yanqi Zhang, Fengyun Yuan, Mintao Mao, Jun Ma   +5 more
doaj   +1 more source

Tregs

, 2015
Regulatory T cell subsets.
Johan Carlsson (826313)
core   +1 more source

Breast Cancer Cells and PD-1/PD-L1 Blockade Upregulate the Expression of PD-1, CTLA-4, TIM-3 and LAG-3 Immune Checkpoints in CD4⁺ T Cells

Vaccines, 2019
Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype, and it exhibits resistance to common breast cancer therapies. Immune checkpoint inhibitors (ICIs) targeting programmed cell death 1 (PD-1) and its ligand, PD-L1, have been
Reem Saleh, Salman M Toor, Sarah Khalaf, Eyad Elkord   +3 more
doaj   +1 more source

Tivozanib mediated inhibition of c-Kit/SCF signaling on Tregs and MDSCs and reversal of tumor induced immune suppression correlates with survival of HCC patients

OncoImmunology, 2020
The immune modulatory effect of tivozanib, a tyrosine kinase inhibitor, and the underlying immune mechanisms impacting survival of HCC patients have not been investigated.
Suresh Gopi Kalathil, Katy Wang, Alan Hutson, Renuka Iyer, Yasmin Thanavala   +4 more
doaj   +1 more source

L1CAM overexpression promotes tumor progression through recruitment of regulatory T cells in esophageal carcinoma

Cancer Biology & Medicine, 2021
Objective: L1 cell adhesion molecule (L1CAM) exhibits oncogenic activity in tumors. However, the link between L1CAM and the tumor microenvironment remains poorly understood in patients with esophageal squamous cell carcinoma (ESCC).
Xuan Zhao, Shasha Liu, Xinfeng Chen, Jianyi Zhao, Feng Li, Qitai Zhao, Tan Xie, Lan Huang, Zhen Zhang, Yu Qi, Yang Yang, Song Zhao, Yi Zhang   +12 more
doaj   +1 more source