Results 201 to 210 of about 8,916 (246)

Effects of Immunoproteasome Inhibition on Adenovirus Pathogenesis

, 2015
Danielle Malitz
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Immunoproteasome components LMP2, PSME1, and PSME2 as novel tissue biomarkers predicting response and survival in neoadjuvant chemoimmunotherapy for resectable NSCLC. [PDF]

Front Immunol
Xie R, Zhai K, Yu J, Zhao M.
europepmc   +1 more source

Plasticity in the structure and assembly of proteasomes. [PDF]

J Biol Chem
Chang AH, Sengupta S, Tomko RJ.
europepmc   +1 more source

Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function

Dinesh Bhattarai, S.W. Lee, Neelam Joshi, Se‐Ran Jun, Sorena B. Lo, Jiang Li, Neriman Gökden, Nirmala Parajuli   +7 more
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Developmental Phase-Specific Molecular Signatures and Signaling Pathways in Cryptorchidism-Induced Testicular Damage. [PDF]

Biomolecules
Wang X, Deng F, Chen Y, Liu X, Li D, Tang X, Lai H, Li Q, Fu W, Liu G, Chen Z, Zhao T.   +11 more
europepmc   +1 more source

Proteomic profiling of bronchoalveolar lavage following human segmental endotoxin challenge-a potential exacerbation model. [PDF]

Sci Rep
Gress C, Müller M, Hohlfeld JM.
europepmc   +1 more source

PI31 is a positive regulator of 20S immunoproteasome assembly.

J Cell Sci
Wang J, Kjellgren A, DeMartino GN.
europepmc   +1 more source

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Immunoproteasomes and immunosenescence

Ageing Research Reviews, 2003
Aging is a complex process which is accompanied with the decline and the reshaping of different functions of the body. In particular the immune system is characterized, during ageing (immunosenescence) by a remodeling of innate immunity (well preserved, up-regulated) and clonotypical immunity (severely altered) and by the occurrence of a chronic ...
Mishto M., Santoro A., Bellavista E., Bonafe M., Monti D., Franceschi C.   +5 more
openaire   +3 more sources

Proteasomes and immunoproteasomes.

Rivista di biologia, 2011
In eukaryotic cells, the protein degradation is a highly regulated and selective process. Membrane-associated or extracellular proteins are degraded in lysosomes, whereas intracellular protein dismantling is primarily non-lysosomal, being realized by complex, not-membrane enclosed and energy-dependent effectors, the proteasomes, localized in both ...
Fietta, Pieranna, Delsante, Giovanni
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On the role of the immunoproteasome in transplant rejection [PDF]

Immunogenetics, 2018
The immunoproteasome is expressed in cells of hematopoietic origin and is induced during inflammation by IFN-γ. Targeting the immunoproteasome with selective inhibitors has been shown to be therapeutically effective in pre-clinical models for autoimmune diseases, colitis-associated cancer formation, and transplantation.
Michael Basler, Jun Li, Marcus Groettrup
exaly   +4 more sources