Results 221 to 230 of about 234,838 (300)

Identification of senescence‐related genes in Parkinson's disease reveals candidate therapeutic targets and pathological processes

Animal Models and Experimental Medicine, EarlyView.
At the genomic level, a large number of differentially expressed genes (DEGs) and aging‐related DEGs have been screened. Ten hub genes, such as IFNγ and IRF7, have been identified and shown potential value in the diagnosis of PD, holding promise as novel biomarkers to facilitate early and precise diagnosis.
Haojie Wu, Tingting Liu, Xiangshu Cheng, Jianshe Wei   +3 more
wiley   +1 more source

Corticosteroid Receptor Modulation in the Dorsal Striatum Prevents Morphine-Induced Place Preference and Reduction in Dopamine Transporter (DAT) Immunoreactivity in Rats. [PDF]

Addict Biol
Raise-Abdullahi P, Rezamohammadi F, Rahmani M, Vafaei AA, Pakdel R, Rashidipour H, Rashidy-Pour A.   +6 more
europepmc   +1 more source

Refining OVCAR‐3 xenograft models of peritoneal carcinomatosis in nu/nu mice: Comparative intraperitoneal implantation strategies and the role of basement membrane matrix

Animal Models and Experimental Medicine, EarlyView.
A refined murine model of advanced ovarian cancer was established by comparing localized preperitoneal implantation and intraperitoneal injection of OVCAR‐3Luc cells. While localized implantation showed limited tumor persistence, intraperitoneal delivery with BME produced sustained diffuse dissemination confirmed by BLI and histology, providing a ...
M. Teresa Perelló‐Trias, Antonio Jose Serrano‐Muñoz, Juan J. Segura‐Sampedro, Adriana M. Quintero‐Duarte, Joana M. Ramis, Marta Monjo   +5 more
wiley   +1 more source

Baseline podocyte‐associated state and persistent cell–matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy

Animal Models and Experimental Medicine, EarlyView.
Two closely related BALB/c substrains exhibit different early responses to adriamycin (ADR)‐induced nephropathy. BALB/cByJcl mice showed lower baseline WT1‐positive nuclei counts and NPHS1 immunoreactivity than BALB/cAJcl mice, together with extracellular matrix and integrin programs that were enriched at baseline and persisted at Day 5.
Ryuya Nakagawa, Masaki Watanabe, Koyuki Kawamoto, Momoka Hiratsuka, Takeru Sasaki, Nobuya Sasaki   +5 more
wiley   +1 more source

PTEN Protein Loss in Diagnostic Prostate Biopsies Is Associated with Gleason Score Upgrading in Radical Prostatectomy. [PDF]

Cancers (Basel)
Kolesarić N, Pezelj I, Tomašković I, Štimac G, Ulamec M, Krušlin B.   +5 more
europepmc   +1 more source

Immunohistochemical and Transcriptomic Assessment of Cytochrome 2J2 in Prostate and Renal Cancer. [PDF]

Cancers (Basel)
Al-Saraireh YM, Alshammari FO, Dmour A, Al-Abadleh AA, Ja'Awin M, Herzallah M, Sawaqed F, Satari AO, Al-Sarayreh SA, Al-Dalain SM, Al-Qtaitat A, Shuneigat JMA, Elsayed AM, Hareedy MS.   +13 more
europepmc   +1 more source

NUP153 immunoreactivity in neuroendocrine neoplasms supports the diagnosis of NET versus NEC and is modulated by post-translational modifications. [PDF]

J Neuroendocrinol
Mattern S, Ali A, Hollfoth V, Bag E, Kluthe K, Herpel E, Bergmann F, Muley T, Meister M, Lehmann-Koch J, Goeppert B, Warth A, Breuhahn K, Bonzheim I, Singer S, Singer K.   +15 more
europepmc   +1 more source

Atlas of gross, histologic, and immunohistologic anatomy of the lymphoid system in Egyptian rousettes (Rousettus aegyptiacus). [PDF]

Vet Res
Elbert JA, Amman BR, Sealy TK, Atimnedi P, Towner JS, Howerth EW.   +5 more
europepmc   +1 more source

Effects of Curcumin on Inflammation in a Rat Model of Diabetic Retinopathy. [PDF]

Life (Basel)
Yu HS, Kang JH, Kim SH, Cho H, Koh SH, Hong EH, Shin YU.   +6 more
europepmc   +1 more source

Tuina Attenuates Pain with Reduced Serum Pain- and Inflammation-Related Mediators and p38 MAPK Phosphorylation in Selected Brain Regions in Rats with Knee Osteoarthritis. [PDF]

J Pain Res
Yang F, Diao J, Li M, Wang Z, Shi M, Fan X, Yang T, Zhou Y, Xu H.   +8 more
europepmc   +1 more source