Results 41 to 50 of about 234,838 (300)

Combination of Selective Immunoassays and Mass Spectrometry to Characterize Preproghrelin-Derived Peptides in Mouse Tissues

open access: yesFrontiers in Neuroscience, 2017
Preproghrelin is a prohormone producing several preproghrelin-derived peptides with structural and functional heterogeneity: acyl ghrelin (AG), desacyl ghrelin (DAG), and obestatin.
Virginie Tolle   +10 more
doaj   +1 more source

Splenic PIM Immunoreactivity.

open access: yes, 2016
Shown are the results of immunohistochemical labeling of the T. parva antigen, PIM, in the spleen. A. The spleen of the control calf lacks PIM immunoreactivity. B.
David A. Schneider (296568)   +5 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Tissue Amyloid Plaque Immunoreactivity (TAPIR) Assay.

open access: yes, 2013
(A) Paraffin-embedded brains sections of Tg mice were incubated with plasma taken from animals that had been immunized with YM3711. Samples were diluted 1∶100 to 1∶1,000.
Naoko Niimi (463963)   +2 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Immunoreactive Calcitonin in Pheochromocytomas

open access: yesExperimental Biology and Medicine, 1980
AbstractImmunoreactive calcitonin (iCT) was evaluated in serum and tumor extracts from four successive, normocalemic patients with sporadic pheochromocytoma to determine how commonly these tumors contain CT-like immunoreactivity. Levels of iCT were measured by a nonequilibrium radioimmunoassay sensitive to both the intact molecule and the 11-32 amino ...
R S, Weinstein, L F, Ide
openaire   +2 more sources

Asymmetric polar Factor VIII immunoreactivity.

open access: yes, 2013
Panel A. Schematic spatial organization of image in Panel B. Panel B. Lung carcinoma. Triangular vascular mirror images. Observe polar immunoreactivity. Panel C. Schematic spatial organization of image in Panel D. Panel D.
Mauricio F. Murillo (37219)   +2 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Influence of Diabetes on Expression of Ezrin and MMP-2 in Gingival Tissue of Patients with Periodontal Disease

open access: yesJournal of Molecular Pathology
Background: The aim of this study was to determine Ezrin and MMP-2 immunohistochemical expressions in the gingival tissue of patients with or without diabetes and to determine the role of the molecular pattern involvement in the evolution of periodontal ...
Ionut Catalin Botezatu   +9 more
doaj   +1 more source

MCT8 immunoreactivity in the rodent mediobasal hypothalamus.

open access: yes, 2013
Low magnification photograph illustrates the presence of MCT8-immunoreactivity associated with tanycytes (A). In the median eminence, strong MCT8-immunoreactivity is observed in tanycyte processes (B, arrows).
László Barna (5064671)   +19 more
core   +1 more source

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