Results 61 to 70 of about 234,838 (300)

Could the Optiplex Borrelia assay replace the traditional, two-step method of diagnosing Lyme disease?

open access: yesAnnals of Agricultural and Environmental Medicine, 2022
Introduction and objective Serological assays for Lyme disease (LD) routinely performed in laboratories often give inconclusive results, thereby making correct diagnosis difficult and delaying treatment.
Iwona Wojciechowska-Koszko   +5 more
doaj   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini   +12 more
wiley   +1 more source

LAMA2 and NELL2 immunoreactivity on ependymoma representative slides.

open access: yes, 2016
(A) LAMA2 positive staining showing focal cytoplasmic immunoreactivity of tumour cells, magnification 100X. (B) LAMA2 positive staining showing focal cytoplasmic immunoreactivity of tumour cells, magnification 200X.
Iwona Filipek (3155454)   +8 more
core   +1 more source

A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy. We identified a novel KCNA1 variant (A401T) in a 16‐year‐old patient with autism spectrum disorder, borderline intellectual disability, and tremor, without episodic ataxia or epilepsy ...
Juan Darío Ortigoza‐Escobar   +7 more
wiley   +1 more source

Immunoreactivity of pan MHC-I epitopes on Crimean-Congo hemorrhagic fever virus glycoprotein C-terminal

open access: yesFrontiers in Immunology
IntroductionCrimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen causing severe hemorrhagic disease with high mortality. The viral glycoprotein Gc mediates membrane fusion and represents a key target of CD8⁺ T-cell responses.
Dongbo Jiang   +22 more
doaj   +1 more source

Characterization of the allergen Sol gem 2 from the fire ant venom, Solenopsis geminata

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2012
Sol i 2 is a potent allergen in Solenopsis invicta venom, and most humans exhibit reactivity to it. The Sol gem 2 allergen found in the venom of the Thai tropical fire ant Solenopsis geminata was analysed in the present study.
S Sukprasert   +5 more
doaj   +1 more source

The Immunoreactivity for VEGF and PEDF in retina.

open access: yes, 2013
No significant immunoreactivity for VEGF and PEDF was found in control retina. I/R injury induced a stronger immunoreactivity for VEGF in retina and diosmin administration relieved this trend.
Qinghua Qiu (406710)   +7 more
core   +1 more source

Additively Manufactured Geometry‐Reconfigurable Soft Neural Probes With Monolithic Multifunctionality

open access: yesAdvanced Functional Materials, EarlyView.
A geometry‐reconfigured additive manufacturing strategy converts planar printed soft materials into soft compact neural probes with integrated hydrogel electrodes and microfluidic channels. The resulting NeuroMAP platform enables scalable multichannel recording, localized chemical delivery, stable in vivo electrophysiological recording, and reduced ...
Hyunjin Lee   +15 more
wiley   +1 more source

A nodular growth on maxillary gingiva

open access: yesIndian Journal of Dental Research, 2012
A case of angiosarcoma of maxilla is presented. The occurrence of angiosarcoma in the oral cavity is a rare incidence and maxilla is one of the rarest sites to be involved.
Amita Aditya, Shailesh Lele
doaj   +1 more source

Summary of the ID, age group, predominant pathological process detected histologically the CNS, and pooled histoscore averages of the protein marker immunoreactivity for the VCN and IC of the dolphins of this study (0—No immunoreactivity; 3—Very intense immunoreactivity).

open access: yes, 2022
Summary of the ID, age group, predominant pathological process detected histologically the CNS, and pooled histoscore averages of the protein marker immunoreactivity for the VCN and IC of the dolphins of this study (0—No immunoreactivity; 3—Very intense ...
Davide Trez (3636283)   +7 more
core   +1 more source

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