Results 91 to 100 of about 30,806 (226)

Sialoadhesin - a macrophage-restricted marker of immunoregulation and inflammation

, 2013
Sialoadhesin (Sn, also known as Siglec-1 and CD169) is a macrophage-restricted cell surface receptor that is conserved across mammals. Sn is a member of the sialic acid-binding IgG-like lectin (Siglec) family of proteins characterized by affinity to ...
Alexander S. G. O'Neill, van den Berg, Timo K., van den Berg, Timo K, Mullen, Gregory E. D., Timo K. van den Berg, Mullen, Gregory E D, Gregory E. D. Mullen, O'Neill, Alexander S G, O'Neill, Alexander S. G.   +8 more
core   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Author Correction: IL-23p19 and CD5 antigen-like form a possible novel heterodimeric cytokine and contribute to experimental autoimmune encephalomyelitis development

Scientific Reports, 2021
Hideaki Hasegawa, Izuru Mizoguchi, Naoko Orii, Shinya Inoue, Yasuhiro Katahira, Toshihiko Yoneto, Mingli Xu, Toru Miyazaki, Takayuki Yoshimoto   +8 more
doaj   +1 more source

Anti‐Inflammatory Effects of Punicic Acid and Its Molecular Mechanisms in RAW264.7 Cells and Zebrafish

Food Safety and Health, EarlyView.
Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang, Caiyun Feng, Mengyao Zhu, Xu Guo, Yingying Chen, Wenwen Hu, Fei Dong, Jinyue Sun, Chao Liu   +8 more
wiley   +1 more source

Murine alveolar macrophages rapidly accumulate intranasally administered SARS-CoV-2 Spike protein leading to neutrophil recruitment and damage

eLife
The trimeric SARS-CoV-2 Spike protein mediates viral attachment facilitating cell entry. Most COVID-19 vaccines direct mammalian cells to express the Spike protein or deliver it directly via inoculation to engender a protective immune response.
Chung Park, Il-Young Hwang, Serena Li-Sue Yan, Sinmanus Vimonpatranon, Danlan Wei, Don Van Ryk, Alexandre Girard, Claudia Cicala, James Arthos, John H Kehrl   +9 more
doaj   +1 more source

Nematode infections in mice - an experimental model of immunoregulation [PDF]

, 2009
There has been a substantial increase in the incidence of autoimmune and allergic diseases in Western countries in the past few decades. However, in the geographic area endemic for parasitic helminth infections, such diseases remain relatively rare.
Jozwicka, K., Doligalska, M., Donskow-Schmelter, K., Donskow-Schmelter, K   +3 more
core   +1 more source

Immunoregulation of experimental autoimmune thyroid disease

, 2005
Experimental autoimmune thyroiditis (EAT) can be induced in mice after challenge with thyroglobulin (Tg) in complete Freund's adjuvant (CFA).
Verginis, Panayotis
core   +1 more source

Serum level of SDF-1α (CXCL12) in chemical victims with respiratory complications

طب جانباز, 2014
Background & Purpose:  Sulfur Mustard (SM)  has been widely used as a chemical warfare agent  against Iranian in Iraq-Iran conflict. Many years after exposure, people who have been exposed to SM are still suffering from its late complications including ...
F. Ayubi, T. Ghazanfari, N. Askari, M.M. Naghizade, M.R. Soroush   +4 more
doaj  

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

Nature Communications, 2016
Tissue-resident macrophages are mostly derived from embryonic progenitors. Scott et al. develop a mouse model to specifically deplete Kupffer cells (KC) in vivoand show that monocyte-derived cells can repopulate KC niche and behave similar to their ...
Charlotte L. Scott, Fang Zheng, Patrick De Baetselier, Liesbet Martens, Yvan Saeys, Sofie De Prijck, Saskia Lippens, Chloé Abels, Steve Schoonooghe, Geert Raes, Nick Devoogdt, Bart N. Lambrecht, Alain Beschin, Martin Guilliams   +13 more
doaj   +1 more source

SARM1: a key multifaceted component in immunoregulation, inflammation and neurodegeneration [PDF]

The downstream signaling pathways of TLR activation involve a family of adaptor proteins, including MYD88, TIRAP, TRIF, TRAM, and SARM1. The first four proteins stimulate inflammatory and antiviral responses, playing crucial roles in innate immunity ...
Beatriz Leocata Ramos, Niels Olsen Saraiva Câmara, Luís Felipe Serra Moreira, Samuel dos Santos Oliveira, Raquel de Souza Vieira, Pedro Henrique Araújo Bandeira, João Vinícius Honório da Silva, Marco Antônio Ataíde Silva   +7 more
core   +1 more source