Results 61 to 70 of about 30,806 (226)

Immunoregulation in the tissues by γδ T cells

, 2003
For a T-cell subset to be classified as immunoregulatory, it might reasonably be predicted that in its absence, animals would experience pathological immune dysregulation. Moreover, reconstitution of the subset should restore normal immune regulation. So
Hayday, A; id_orcid, Robert Tigelaar, Adrian Hayday, Tigelaar, R   +3 more
core   +1 more source

DataSheet_1_Differential expression and correlation of immunoregulation related piRNA in rheumatoid arthritis.xlsx

, 2023
BackgroundAlthough PIWI-interacting RNAs (piRNAs) have recently been associated with germline development and many human diseases, their expression pattern and relationship in autoimmune diseases remain indistinct.
Huiling Tan (500089), Zhuochun Huang (779527), Bin Yang (103252), Ruyu Ren (15997958), Yuanyi Wang (1793113)   +4 more
core   +1 more source

HLA alleles predisposing to autoimmunity are linked to impaired immunoregulation in patients with juvenile autoimmune liver disease and in their first-degree relatives

Background & aims Juvenile autoimmune liver disease (JAILD) comprises autoimmune hepatitis and autoimmune sclerosing cholangitis. JAILD-predisposing genes include HLA-DR3,DR7, DR13 and haplotype A1-B8-DR3.
Grammatikopoulos, T., Grammatikopoulos, Tassos, Wang, P., Samyn, Marianne, Graham, Jonathon, Ma, Yun, Huang, X., Ma, Y., Hussain, Munther, Wang, Pengyun, Liberal, Rodrigo, Vergani, D., Heneghan, Michael, Hussain, M., Heneghan, M., Hadzic, D., Mieli-Vergani, G., Longhi, Maria Serena, Huang, Xiaohong, Gabeta, S., Hadzic, Dino, Liberal, R., Mieli-Vergani, Giorgina, Samyn, M., Longhi, M.S., Blackmore, Laura Jayne, Gabeta, Stella, Blackmore, L.J., Yuksel, M., Graham, J., Vergani, Diego, Yuksel, Muhammed   +31 more
core   +1 more source

Sympathetic immunoregulation: difference between high- and low-responder animals

, 1982
A quantitative relationship is reported between the magnitude of the immune response of rats to sheep red blood cells and diminution of splenic norepinephrine (NE).
E. Sorkin, H. O. Besedovsky, M. Da Prada, G. P. Bondiolotti, A. del Rey   +4 more
core   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Epitope mapping and kinetics of CD4 T cell immunity to pneumonia virus of mice in the C57BL/6 strain

Scientific Reports, 2017
Pneumonia virus of mice (PVM) infection has been widely used as a rodent model to study the closely related human respiratory syncytial virus (hRSV). While T cells are indispensable for viral clearance, they also contribute to immunopathology.
Lana Vandersarren, Cedric Bosteels, Manon Vanheerswynghels, James J. Moon, Andrew J. Easton, Gert Van Isterdael, Sophie Janssens, Bart N. Lambrecht, Mary J. van Helden   +8 more
doaj   +1 more source

IMMUNOREGULATION OF HEPATITIS B VIRUS INFECTION : RATIONALE AND CLINICAL APPLICATION [PDF]

, 2012
2012-08Hepatitis B virus (HBV) is susceptible to the cellular immune responses, especially to the signal of interferon (IFN)-γ. The action of IFN-γ is pleiotropic, and causes downregulation of HBV in protein, RNA, and possibly DNA levels.
ISHIKAWA, TETSUYA
core   +1 more source

A Postbiotic‐Inducing Ganoderma applanatum Polysaccharide Repairs the Intestinal Barrier via a Phocaeicola vulgatus ‐ Tridecylic Acid Axis

Advanced Science, EarlyView.
This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang, Miaoyu Li, Tiantian Li, Xiaojie Zang, Haiyang Shi, Yaru Liu, Chengcheng Zhang, Jianxin Zhao, Qixiao Zhai, Wei Chen, Fengwei Tian   +10 more
wiley   +1 more source

Functional Mechanisms of Treg in the Context of HIV Infection and the Janus Face of Immune Suppression

Frontiers in Immunology, 2016
Regulatory T cells (Tregs) play an important role in infections, by modulating host immune responses and avoiding the overreactive immunity that in the case of human immunodeficiency virus (HIV) infection leads to a marked erosion and deregulation of the
Jacobo López-Abente, Rafael Correa-Rocha, Marjorie Pion   +2 more
doaj   +1 more source

Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological Niche

Advanced Science, EarlyView.
A subcutaneous synthetic immunological niche (IN) enables serial, minimally invasive monitoring of immune responses after islet transplantation. Flow cytometry and transcriptomic profiling of the IN reveal immune‐cell programs associated with graft acceptance and distinct types of rejection.
Jyotirmoy Roy, Abdalmonam Jadou Nejma, Mohammad Tarique, Amod Talekar, Shengli Wu, Brianna Ha, Yifei Jiang, Esma S. Yolcu, Lonnie D. Shea   +8 more
wiley   +1 more source