Reinstating endogenous antitumor immunity: The concept of therapeutic management of cancer
Strong evidence points to the role of cancer immunoediting and tumor immune infiltrates in regulating cancer progression. By understanding the immune tumor microenvironment, we can now target key pathways that suppress endogenous antitumor responses ...
Pistamaltzian Nikolaos F. +2 more
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Classificação Immunoscore em Carcinoma Colorretal
Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de ...
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In order to validate the immunoscore, an international consortium with twenty-three centers involved was initiated in 2012. It is planned to test immunoscore on tumor samples from several thousand colorectal cancer patients.
Agnieszka Pastuła, Pastula, Agnieszka,
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Background In clinical practice, lymph node status has an important impact on colon cancer (CC) management and treatment. The role of the tumor microenvironment collagen score and immunoscore in colon cancer lymph node metastasis remains unknown. Methods
Chenyan Long +7 more
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[Immunoscore and Its Predictive Value for Colorectal Cancer].
Recent studies suggest that immune classification (immune-score) in cancer patients has a prognostic value in some cases that seems to be superior to the AJCC/ UICC TNM classification. The clinical outcome can vary significantly among patients with a particular diagnosis within the same TNM stage.
E, Závadová +8 more
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Immunoscore based on CD3<sup>+</sup> and cytotoxic CD8<sup>+</sup> T-lymphocyte densities predicts prognosis and chemotherapy efficacy in esophageal squamous cell carcinoma. [PDF]
Fan NJ +10 more
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Immunoscore on most of ONCOBIOME cohorts
Immunoscore on most of ONCOBIOME cohorts using a standardized ...
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Integrative Profiling of Tumor and Blood Microenvironments to Uncover Molecular and Immune Determinants of Prognosis and Treatment Efficacy in Metastatic Colorectal Cancer. [PDF]
Benidovskaya E +4 more
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Artificial intelligence-powered H&E-based quantification of spatial tumor-infiltrating lymphocyte distribution identifies prognostic immune niches in colorectal cancer. [PDF]
Koh HH +9 more
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