Results 141 to 150 of about 3,200 (166)

The correlation of immunoscore and frailty in colorectal cancer

International Journal of Clinical Oncology, 2021
The Immunoscore is a useful prognostic and predictive factor for colorectal cancer. Frailty predicts overall and recurrence-free survival following resection of colorectal cancer, and the immunosuppressive state of frailty might affect tumor progression.
Toshihiro Nakao, Mitsuo Shimada, Kozo Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuma Wada, Toshiaki Yoshimoto, Syoko Yamashita, Yosuke Iwakawa   +10 more
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Immunoscore and its introduction in clinical practice

The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2020
Current cancer classification is based on intrinsic tumor parameters such as characteristic of tumor cells, tumor progression, tumor invasion and the presence of distant metastases, as summarized by the AJCC/UICC-TNM stratification system. There is currently no immune-based classification of cancer.
Jérôme, Galon, Anastasia, Lanzi
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ImmunoScore Signature

Annals of Surgery, 2018
We postulated that the ImmunoScore (IS) could markedly improve the prediction of postsurgical survival and chemotherapeutic benefits in gastric cancer (GC).A prediction model for GC patients was developed using data from 879 consecutive patients.The expression of 27 immune features was detected in 251 specimens by using immunohistochemistry, and a 5 ...
Yuming, Jiang, Qi, Zhang, Yanfeng, Hu, Tuanjie, Li, Jiang, Yu, Liying, Zhao, Gengtai, Ye, Haijun, Deng, Tingyu, Mou, Shirong, Cai, Zhiwei, Zhou, Hao, Liu, Guihua, Chen, Guoxin, Li, Xiaolong, Qi   +14 more
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Immunoscoring the lymphocytic infiltration in carcinoid tumours

Histopathology, 2017
The interesting article by Swarts et al. concerns the limited additive prognostic value of Ki-67 proliferative index in patients with pulmonary carcinoids.1 We should like to draw attention to another histopathological aspect of pulmonary carcinoids, namely tumour-infiltrating lymphocytes (TIL) This article is protected by copyright.
Luca Roncati, Antonio Manenti, Francesco Piscioli, Teresa Pusiol, Giuseppe Barbolini   +4 more
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Prognostic Value of the Neo-Immunoscore in Renal Cell Carcinoma [PDF]

Frontiers in Oncology, 2019
Objective: This study evaluated the prognostic value of the newly-built Immunoscore (neo-Immunoscore) in patients with renal cell carcinoma (RCC). Methods: Eighty-two patients with RCC were enrolled in this study. Their 3- and 5-year survival rates and overall survival (OS) were evaluated.
Xiubao Ren, Feng Wei, Zizhong Yang
exaly   +4 more sources

The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy

Nature Reviews Cancer, 2020
The international American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) tumour-node-metastasis (TNM) staging system provides the current guidelines for the classification of cancer. However, among patients within the same stage, the clinical outcome can be very different.
Daniela Bruni, Helen K. Angell, Jérôme Galon   +2 more
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[Intratumoral immune microenvironment and survival: the immunoscore].

Medecine sciences : M/S, 2014
The natural history of cancer involves interactions between the tumor and the host immune system. In humans, clinical and experimental data support the existence of a natural immune response against cancer. We provided evidence that the type, the density and the location of immune cells within the tumor strongly influence the prognosis, independently ...
Jérôme, Galon, Gabriela, Bindea, Bernhard, Mlecnik, Helen, Angell, Christine, Lagorce, Ana Maria, Todosi, Anne, Berger, Franck, Pagès   +7 more
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Immunoscore as new possible approach for the classification of melanoma.

Journal of Clinical Oncology, 2014
e20020 Background: Immune cells infiltrating the tumor microenvironment (TILs) may either limit or promote tumor progression.
Mariaelena Capone, Gabriele Madonna, Noemi Sebastiao, Jean Bird, Fabrizio Di Ayala, Corrado Caraco, Gennaro Ciliberto, Bonnie LaFleur, Nicola Mozzillo, Gerardo Botti, Alisa Tubbs, Paolo Antonio Ascierto   +11 more
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Prognostic and Predictive Values of the Immunoscore in Patients with Rectal Cancer

Clinical Cancer Research, 2014
Abstract Purpose: To determine whether the tumor immune infiltrate, as recently evaluated with the Immunoscore methodology, could be a useful prognostic marker in patients with rectal cancers. Experimental design: The influence of the immune infiltrate on patient's outcome was investigated in patients with or without
Maria-Gabriela, Anitei, Guy, Zeitoun, Bernhard, Mlecnik, Florence, Marliot, Nacilla, Haicheur, Ana-Maria, Todosi, Amos, Kirilovsky, Christine, Lagorce, Gabriela, Bindea, Dan, Ferariu, Mihai, Danciu, Patrick, Bruneval, Viorel, Scripcariu, Jean-Marc, Chevallier, Franck, Zinzindohoué, Anne, Berger, Jérôme, Galon, Franck, Pagès   +17 more
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Contribution of Immunoscore to Survival Prediction in Pancreatic Ductal Adenocarcinoma

Anticancer Research
The presence of tumor-infiltrating lymphocytes (TILs) has been demonstrated as a prognostic factor in colorectal cancer after surgical resection of malignancy, but knowledge on their role in pancreatic cancer is lacking. The Immunoscore (IS) assesses TILs at the core of the tumor (CT) and invasive margin (IM) and is being evaluated as a new concept in ...
Haruki, Mori, Toru, Miyake, Hiromitsu, Maehira, Masanori, Shiohara, Hiroya, Iida, Nobuhito, Nitta, Masaji, Tani   +6 more
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