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The consensus immunoscore: toward a new classification of colorectal cancer [PDF]
In its latest edition, the WHO classification of the Digestive System Tumors introduced for the first time the immune response as essential and desirable diagnostic criteria for colorectal cancer.
Jérôme Galon, Franck Pagès
exaly +5 more sources
Clinical Performance of the Consensus Immunoscore in Colon Cancer in the Asian Population from the Multicenter International SITC Study [PDF]
BACKGROUND: In this study, we evaluated the prognostic value of Immunoscore in patients with stage I−III colon cancer (CC) in the Asian population. These patients were originally included in an international study led by the Society for Immunotherapy of ...
Jiun-Kae Lee +2 more
exaly +7 more sources
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study [PDF]
The estimation of risk of recurrence for patients with colon carcinoma must be improved. A robust immune score quantification is needed to introduce immune parameters into cancer classification.
Gabriela Bindea +2 more
exaly +5 more sources
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The correlation of immunoscore and frailty in colorectal cancer
International Journal of Clinical Oncology, 2021The Immunoscore is a useful prognostic and predictive factor for colorectal cancer. Frailty predicts overall and recurrence-free survival following resection of colorectal cancer, and the immunosuppressive state of frailty might affect tumor progression.
Toshihiro Nakao +10 more
openaire +2 more sources
Immunoscore and its introduction in clinical practice
The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2020Current cancer classification is based on intrinsic tumor parameters such as characteristic of tumor cells, tumor progression, tumor invasion and the presence of distant metastases, as summarized by the AJCC/UICC-TNM stratification system. There is currently no immune-based classification of cancer.
Jérôme, Galon, Anastasia, Lanzi
openaire +2 more sources
Annals of Surgery, 2018
We postulated that the ImmunoScore (IS) could markedly improve the prediction of postsurgical survival and chemotherapeutic benefits in gastric cancer (GC).A prediction model for GC patients was developed using data from 879 consecutive patients.The expression of 27 immune features was detected in 251 specimens by using immunohistochemistry, and a 5 ...
Yuming, Jiang +14 more
openaire +2 more sources
We postulated that the ImmunoScore (IS) could markedly improve the prediction of postsurgical survival and chemotherapeutic benefits in gastric cancer (GC).A prediction model for GC patients was developed using data from 879 consecutive patients.The expression of 27 immune features was detected in 251 specimens by using immunohistochemistry, and a 5 ...
Yuming, Jiang +14 more
openaire +2 more sources
Immunoscoring the lymphocytic infiltration in carcinoid tumours
Histopathology, 2017The interesting article by Swarts et al. concerns the limited additive prognostic value of Ki-67 proliferative index in patients with pulmonary carcinoids.1 We should like to draw attention to another histopathological aspect of pulmonary carcinoids, namely tumour-infiltrating lymphocytes (TIL) This article is protected by copyright.
Luca Roncati +4 more
openaire +2 more sources
The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy
Nature Reviews Cancer, 2020The international American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) tumour-node-metastasis (TNM) staging system provides the current guidelines for the classification of cancer. However, among patients within the same stage, the clinical outcome can be very different.
Daniela Bruni +2 more
openaire +2 more sources

