Results 171 to 180 of about 3,957 (191)

[Intratumoral immune microenvironment and survival: the immunoscore].

Medecine sciences : M/S, 2014
The natural history of cancer involves interactions between the tumor and the host immune system. In humans, clinical and experimental data support the existence of a natural immune response against cancer. We provided evidence that the type, the density and the location of immune cells within the tumor strongly influence the prognosis, independently ...
Jérôme, Galon, Gabriela, Bindea, Bernhard, Mlecnik, Helen, Angell, Christine, Lagorce, Ana Maria, Todosi, Anne, Berger, Franck, Pagès   +7 more
openaire   +2 more sources

Prognostic and Predictive Values of the Immunoscore in Patients with Rectal Cancer

Clinical Cancer Research, 2014
Abstract Purpose: To determine whether the tumor immune infiltrate, as recently evaluated with the Immunoscore methodology, could be a useful prognostic marker in patients with rectal cancers. Experimental design: The influence of the immune infiltrate on patient's outcome was investigated in patients with or without
Maria-Gabriela, Anitei, Guy, Zeitoun, Bernhard, Mlecnik, Florence, Marliot, Nacilla, Haicheur, Ana-Maria, Todosi, Amos, Kirilovsky, Christine, Lagorce, Gabriela, Bindea, Dan, Ferariu, Mihai, Danciu, Patrick, Bruneval, Viorel, Scripcariu, Jean-Marc, Chevallier, Franck, Zinzindohoué, Anne, Berger, Jérôme, Galon, Franck, Pagès   +17 more
openaire   +2 more sources

Contribution of Immunoscore to Survival Prediction in Pancreatic Ductal Adenocarcinoma

Anticancer Research
The presence of tumor-infiltrating lymphocytes (TILs) has been demonstrated as a prognostic factor in colorectal cancer after surgical resection of malignancy, but knowledge on their role in pancreatic cancer is lacking. The Immunoscore (IS) assesses TILs at the core of the tumor (CT) and invasive margin (IM) and is being evaluated as a new concept in ...
Haruki, Mori, Toru, Miyake, Hiromitsu, Maehira, Masanori, Shiohara, Hiroya, Iida, Nobuhito, Nitta, Masaji, Tani   +6 more
openaire   +2 more sources

Towards developing an immunoscore for gliomas

Gliomas represent the most prevalent form of primary brain cancer. The classification of gliomas is based on histological data, genetic data, such as mutations, and methylation data. The most common predictors are IDH 1/2 mutations, with IDH-wildtype gliomas, classified as glioblastomas (GBMs), being the most malignant type of glioma with an overall ...
openaire   +1 more source

Immunoscore provides a more accurate prognosis

Nature Reviews Clinical Oncology, 2018
openaire   +2 more sources

Immunoscore immune checkpoint using spatial quantitative analysis of CD8 and PD-L1 markers is predictive of the efficacy of anti- PD1/PD-L1 immunotherapy in non-small cell lung cancer

EBioMedicine, 2023
Pascale Tomasini, Thomas Sbarrato, Frederic Bibeau   +2 more
exaly  

The Immunoscore: A New Tool for Cancer Prognosis

Clinical OMICs, 2014
Merrilyn Datta, Wendy Parenteau
openaire   +1 more source

Prognostic and predictive value of the Immunoscore in stage III colon cancer patients treated with oxaliplatin in the prospective IDEA France PRODIGE-GERCOR cohort study†

Annals of Oncology, 2020
Franck Pagès, Jean-François Emile, J Galon   +2 more
exaly  

Histopathological growth patterns correlate with the immunoscore in colorectal cancer liver metastasis patients after hepatectomy

Cancer Immunology, Immunotherapy, 2020
Yun Zheng, De-Shen Wang, Rui-Hua Xu
exaly  

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