Results 91 to 100 of about 556,132 (392)

Considering local immunity for innovative immunomodulatory approaches: pulmonary sepsis as a use case

open access: yesFrontiers in Immunology
Owing to faster identification of sepsis and improvement of patient management, most septic patients now survive the early phase of sepsis. Therefore, one of the major challenges in sepsis management today is to identify those patients at risk and ...
Emilie Vernay   +14 more
doaj   +1 more source

Comprehensive comparison of three different immunosuppressive regimens for liver transplant patients with hepatocellular carcinoma: steroid-free immunosuppression, induction immunosuppression and standard immunosuppression. [PDF]

open access: yesPLoS ONE, 2015
The different choices of immunosuppression (IS) regimens influenced the outcomes of liver transplantation. Steroid was applied as a standard IS to prevent and treat rejections. However, steroid-related complications were increasingly prominent.
Yuan-Yuan Liu   +10 more
doaj   +1 more source

Posttransplant lymphoproliferative disorders in neuronal xenotransplanted macaques [PDF]

open access: yes, 2016
Posttransplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of lymphoid proliferations that occur in the setting of depressed T-cell function due to immunosuppressive therapy used following solid organ transplantation, hematopoietic ...
Aron Badin, R.   +12 more
core   +1 more source

Pediatric Liver Transplantation: Then and Now [PDF]

open access: yes, 2020
This paper reviews the past 50 years of liver transplantation in children from the perspective of patient demographics, perioperative patient management, surgical techniques, immunosuppression and patient ...
Banh, DPT   +4 more
core   +1 more source

Surgical trauma‐induced immunosuppression in cancer: Recent advances and the potential therapies

open access: yesClinical and Translational Medicine, 2020
Surgical resection remains the mainstay treatment for solid cancers, especially for localized disease. However, the postoperative immunosuppression provides a window for cancer cell proliferation and awakening dormant cancer cells, leading to rapid ...
F. Tang, Y. Tie, C. Tu, Xiawei Wei
semanticscholar   +1 more source

Beyond Inflammation: Why Understanding the Brain Matters in Inflammatory Arthritis

open access: yesArthritis Care &Research, EarlyView.
Persistent pain remains a major challenge in inflammatory arthritis, even when joint inflammation is well controlled. Pain and associated symptoms such as fatigue cannot be explained by peripheral inflammation alone but reflect altered central pain processing. These changes may arise through “top‐down” mechanisms, reflecting pre‐existing dysfunction in
Eoin M. Kelleher   +2 more
wiley   +1 more source

Whole blood ratio of CDK1/CX3CR1 mRNA expression combined to lactate refines the prediction of ICU mortality in septic patients in the Sepsis-3 era: a proof-of-concept study

open access: yesFrontiers in Medicine
BackgroundTranscriptomics biomarkers have been widely used to predict mortality in patients with sepsis. However, the association between mRNA levels and outcomes shows substantial variability over the course of sepsis, limiting their predictive ...
Marie-Angélique Cazalis   +12 more
doaj   +1 more source

Orthotopic liver transplantation in U.S. veterans under primary tacrolimus immunosupression. [PDF]

open access: yes, 1996
The evolution and refinement of surgical techniques, per ioperative patient care, and immunosuppression hav~ estab~ished orthoto~ic li~er transplantation (OLTX) as a ~ighly successful therapeutic modality for patients wrth end-stage hver disease.
Doyle, HR   +7 more
core  

MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY

open access: yesArthritis Care &Research, Accepted Article.
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

Kidney after nonrenal transplantation-the impact of alemtuzumab induction [PDF]

open access: yes, 2009
BACKGROUND.: Calcineurin inhibitor nephrotoxicity in nonrenal allograft recipients can lead to end-stage renal disease and the need for kidney transplantation. We sought to evaluate the role of alemtuzumab induction in this population.
Amit Basu   +27 more
core   +1 more source

Home - About - Disclaimer - Privacy