Results 101 to 110 of about 458,490 (361)
S282: A RANDOMIZED CONTROLLED CLINICAL TRIAL DEMONSTRATES THAT PLASMA FROM CONVALESCENT AND VACCINATED DONORS IMPROVES OUTCOME OF COVID-19 IN PATIENTS WITH HEMATOLOGICAL DISEASE, CANCER OR IMMUNOSUPPRESSION
, 2022 C. Müller-Tidow, Maike Janssen, U. Schäkel, J. Gall, Albrecht Leo, P. Stelmach, Johannes Krisam, Lukas Baumann, Julia Stermann, U. Merle, Martin Zeier, M.A. Weigand, Lars Bullinger, Jens Schrezenmeier, Martin Bornhäuser, Nael Alakel, O. Witzke, Tammy Wolf, M. J. Vehreschild, Stefan Schmiedel, Marylyn M. Addo, F. Herth, M Kreutner, Phil‐Robin Tepasse, Bernd Hertenstein, Matthias Hänel, Anke Morgner, Michael Kiehl, Olaf Hopfer, M.-A. Wattad, C Schimanski, Cihan Celik, Thorsten Pohle, M. Ruhe, Werner Kern, A Schmitt, M. Schmitt, P. Dreger, H.-M. Lorenz, M. Souto-Carneiro, Neils Halama, S. Meuer, H.-G. Kräusslich, B. Müller, Ralf Bartenschlager, J. Klemmer, K. Kriegsmann, R. F. Schlenk, Claudia M. Denkinger +48 moreopenalex +1 more sourceSpatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway
Advanced Science, EarlyView.Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen +15 morewiley +1 more sourceData from CYP4F2-Catalyzed Metabolism of Arachidonic Acid Promotes Stromal Cell-Mediated Immunosuppression in Non–Small Cell Lung Cancer
, 2023 Xuehan Chen, Yanzhuo Liu, Yang Wang, Chenlong Wang, Xuewei Chen, Yu Xiong, Lilong Liu, Xi Yuan, Honglin Tang, Chong Shu, Jing Zhang, Austin M. Guo, Honglei Chen, Jing Yang +13 moreopenalex +1 more sourceEngineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy
Advanced Science, EarlyView.IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract
Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang +15 morewiley +1 more sourceRETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.Ren‐Qi Yao, Chao Ren, Li‐Yu Zheng, Jing‐Yan Li, Wen‐Feng Wu, Yu‐Xuan Li, Li‐Xue Wang, Yu Duan, Lu Wang, Shuang‐Qing Liu, Peng‐Yi He, Peng‐Yue Zhao, Sen Tong, Zhi‐Xuan Li, Tuo Zhang, Meng‐Yao Wu, Shu‐Ting Wei, Ning Dong, Yao Wu, Hui Zhang, Xiao‐Mei Zhu, Zi‐Cheng Zhang, Guo‐Sheng Wu, Zhao‐Fan Xia, Xiao‐Hui Du, Hong‐Jun Kang, Zui Zou, Dao‐Lin Tang, Yong‐Ming Yao +28 morewiley +1 more sourceSupplementary Figure 9 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
, 2023 Xinming Su, Alison K. Esser, Sarah R. Amend, Jingyu Xiang, Yalin Xu, Michael H. Ross, Gregory C. Fox, Takayuki Kobayashi, Veronica Steri, Kirsten Roomp, Francesca Fontana, Michelle A. Hurchla, Brett L. Knolhoff, Melissa A. Meyer, Elizabeth A. Morgan, Julia C. Tomasson, Joshua S. Novack, Wei Zou, Roberta Faccio, Deborah V. Novack, Stephen Robinson, Steven L. Teitelbaum, David G. DeNardo, Jochen G. Schneider, Katherine N. Weilbaecher +24 moreopenalex +1 more source