Results 111 to 120 of about 353,556 (317)
Whole Exome Sequencing to Estimate Alloreactivity Potential Between Donors and Recipients in Stem Cell Transplantation [PDF]
arXiv, 2014 Whole exome sequencing was performed on HLA-matched stem cell donors and transplant recipients to measure sequence variation contributing to minor histocompatibility antigen differences between the two. A large number of nonsynonymous single nucleotide polymorphisms were identified in each of the nine unique donor-recipient pairs tested. This variation
arxiv
Advanced Science, EarlyView.This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi +18 more
wiley +1 more source
COVID-19: consider cytokine storm syndromes and immunosuppression
The Lancet, 2020 P. Mehta +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou +35 more
wiley +1 more source
Medication non adherence: finding solutions through design thinking approach [PDF]
arXiv, 2017 Medical non-adherence increasingly is recognized as a major medical health problem. Approximately 50% of patients do not take their medications as prescribed and such poor adherence has been shown to result in complications, death, and increased health care costs.
arxiv
Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia
New England Journal of Medicine, 2022 R. Peffault de Latour +49 more
semanticscholar +1 more source
Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles
Advanced Science, EarlyView.Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon +25 more
wiley +1 more source
Immunopathogenesis in Psoriasis through a Density-type Mathematical Model [PDF]
WSEAS Transactions on Mathematics, Issue 5, Volume 11, May 2012,
pp 440 - 450, 2019 Disease psoriasis occurs as chronic inflammation of skin and appears as scaly red lesions on skin surface. Advent of several immunosuppressive drugs established that the disease stems from immuno-pathogenic disorder in human blood. Cell biological as well as clinical research on the disease reveals that the helper T-cells and other Leucocytes ...
arxiv
Immunosuppression during Acute Murine Cytomegalovirus Infection [PDF]
, 1968 June E. Osborn +2 more
openalex +1 more source
World Journal of Gastroenterology, 2016 In patients with inflammatory bowel disease (IBD), chronic inflammation is a major risk factor for the development of gastrointestinal malignancies. The pathogenesis of colitis-associated cancer is distinct from sporadic colorectal carcinoma and the ...
J. Axelrad, S. Lichtiger, V. Yajnik
semanticscholar +1 more source