Results 171 to 180 of about 392,479 (342)

Checkpoint inhibitor effectiveness after corticosteroids and second-line immunosuppressants for immune-related adverse events in non-small-cell lung cancer. [PDF]

ESMO Open
van Dijk EJ, Smeenk MM, Bensch F, Sadowksa AM, Verschueren MV, Verhaert M, Llobell A, Suzuki Y, Liew DFL, Takeji A, Maria ATJ, Peters BJM, Garcia Morillo JS, Chatzidionysiou K, Lidar M, van der Hout EC, Aspeslagh S, Herder GJM, van de Garde EMW, Hendriks LEL, Hijmering-Kappelle LBM, Theelen WSME, Suijkerbuijk KPM, Verheijden RJ.   +23 more
europepmc   +1 more source

P5406Is it safe to discontinue immunosuppression in cardiac sarcoidosis? [PDF]

, 2017
Piia Simonen, Jukka Lehtonen, Markku Kupari   +2 more
openalex   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Intensification of Antiretroviral Therapy through Addition of Enfuvirtide in Naive HIV-1-Infected Patients with Severe Immunosuppression Does Not Improve Immunological Response: Results of a Randomized Multicenter Trial (ANRS 130 Apollo) [PDF]

, 2012
Véronique Joly, Catherine Fagard, Carine Grondin, Diane Descamps, Yazdan Yazdanpanah, Charlotte Charpentier, Nathalie Verdière, Sophie Tabuteau, François Raffi, André Cabié, Geneviève Chêne, Patrick Yéni, the ANRS 130 Apollo Trial Group   +12 more
openalex   +1 more source

Complex assessment of immunosuppression effects in prevention and treatment of adhesive disease, an experiment

, 2022
Dauren Auzhanov, Meirbek Aimagambetov, Омаров Н.Б.   +2 more
openalex   +1 more source

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Echocardiographic Pulmonary Hypertension in Patients Positive for Myositis-Specific and Myositis-Associated Antibodies. [PDF]

J Clin Med
Akopyan K, Peterson J, Amoda O, Khasawneh M, Hadigal S, Harden C, Manjarres DG, Reddy R, Pais F.   +8 more
europepmc   +1 more source

Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide.

Cell Stem Cell, 2008
G. Ren, Liying Zhang, Xin Zhao, Guangwu Xu, Yingyu Zhang, A. Roberts, R. Zhao, Yufang Shi   +7 more
semanticscholar   +1 more source

Sa1811 – Genotype and Posst-Operative Immunosuppression Impact Surgical Recurrence in Crohn's Disease

, 2019
Mark Salem, Dalin Li, Mark E. Gerich, Shaohong Yang, Eric Vasiliauskas, Gaurav Syal, Christina Ha, Nirupama Bonthala, Shervin Rabizadeh, Karen Zaghiyan, Talin Haritunians, Gil Melmed, Stephan Targan, Phillip Fleshner, Dermot McGovern   +14 more
openalex   +1 more source