Results 251 to 260 of about 521,863 (391)

Chronic immunosuppression, Australia antigenemia, and hepatitis. [PDF]

, 1972
Putnam, CW, Starzl, TE
core  

Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation

Advanced Science, EarlyView.
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu, Jeffrey Galley, Jason Pizzini, Elena Musteata, Martin V. Douglas, Walter J. Chazin, Eric P. Skaar, Jeffrey J. Tabor, Robert A. Britton   +8 more
wiley   +1 more source

Recombinant Zoster Vaccine Use to Prevent Recurrent Shingles in an Adolescent Renal Transplant Recipient. [PDF]

Cureus
Nikfarjam N, Grimm P.
europepmc   +1 more source

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival.

Cancer Cell, 2015
B. Özdemir, Tsvetelina Pentcheva-Hoang, Julienne L. Carstens, Xiaofeng Zheng, Chia-Chin Wu, T. Simpson, Hanane Laklai, H. Sugimoto, C. Kahlert, S. Novitskiy, A. De Jesus-Acosta, Padmanee Sharma, P. Heidari, U. Mahmood, L. Chin, H. Moses, V. Weaver, A. Maitra, J. Allison, Valerie S. LeBleu, R. Kalluri   +20 more
semanticscholar   +1 more source

Exosomal CMTM4 Induces Immunosuppressive Macrophages to Promote Ovarian Cancer Progression and Attenuate Anti‐PD‐1 Immunotherapy

Advanced Science, EarlyView.
In ovarian tumors with high CMTM4 expression, exosomes transfer CMTM4 to macrophages, upregulating ICAM1 and promoting M2 polarization via p65 nuclear translocation. This suppresses immunity by increasing PD‐1 and Tregs while reducing CD8+ T cells.
Bo Yin, Jianyi Ding, Jie Liu, Haoran Hu, Yashi Zhu, Meiqin Yang, Huijuan Zhou, Baoyou Huang, Tiefeng Huang, Mengjie Li, Yinyan He, Ang Li, Lingfei Han   +12 more
wiley   +1 more source

Advocating for the recognition of underlying immunosuppression in critical illness

EClinicalMedicine
Summary: Immunosuppression, characterised by impaired immune function, significantly influences infection risk and ICU admissions in critically ill patients.
Ignacio Martin-Loeches, Sascha David, Frédéric Pène, Louis Kreitmann, Lene Russel, Kathryn Puxty, João Santos Silva, Ana Vagos Mata, Ben Creagh-Brown, Pedro Castro, Jorge Salluh, Loreto Vidaur-Tello, Saad Nseir, Elie Azoulay   +13 more
doaj  

Immunosuppression and hepatitis after renal transplantation. [PDF]

, 1979

openalex   +1 more source

Is it currently possible to evaluate the risk posed by PERVs for clinical xenotransplantation? [PDF]

, 2018
Denner, Joachim, Schuurman, Henk-Jan, Scobie, Linda   +2 more
core   +1 more source

Covalent Organic Frameworks‐Delivered Reuterin Drives Trained Immunity in Tumor‐Associated Macrophages to Enhance Melanoma Immunotherapy via Glycerophospholipid Metabolism

Advanced Science, EarlyView.
Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang, Xiao‐Mei Zhang, Xi Wu, Cheng‐Kai Zhou, Zhen‐Zhen Liu, Xue‐Yue Luo, Liang Zhang, Wei Chen, Yong‐Jun Yang   +8 more
wiley   +1 more source

Identification of lncRNAs in peripheral blood mononuclear cells associated with sepsis immunosuppression based on weighted gene co-expression network analysis. [PDF]

Hereditas
Zhang W, Li Y, Li G, Zhang A, Sun W.
europepmc   +1 more source