Results 31 to 40 of about 353,556 (317)
Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections
JCI Insight, 2020 COVID-19–associated morbidity and mortality have been attributed to a pathologic host response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and failure of host protective immunity that results in unrestrained viral ...
Kenneth E. Remy +20 more
semanticscholar +1 more source
Predicting Dosage of Immunosuppressant Drugs After Kidney Transplantation Using Machine Learning [PDF]
arXiv, 2023 While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage variance based on each patient's unique physiology, nephrologists face numerous difficulties when determining the precise
arxiv
Transplantation Direct, 2023 Background. Few studies have addressed immunosuppression management after allograft failure (AF). Immunosuppression withdrawal to minimize complications must be balanced with the risk of sensitization and potentially reduced retransplantation.
Suryanarayanan Balakrishnan, MD +6 more
doaj +1 more source
Optimal Kidney Exchange with Immunosuppressants [PDF]
arXiv, 2021 Algorithms for exchange of kidneys is one of the key successful applications in market design, artificial intelligence, and operations research. Potent immunosuppressant drugs suppress the body's ability to reject a transplanted organ up to the point that a transplant across blood- or tissue-type incompatibility becomes possible.
arxiv
Endogenous Retroviruses Transcriptional Modulation After Severe Infection, Trauma and Burn
Frontiers in Immunology, 2019 Although human endogenous retroviruses (HERVs) expression is a growing subject of interest, no study focused before on specific endogenous retroviruses loci activation in severely injured patients.
Olivier Tabone +18 more
doaj +1 more source
Metabolites, 2023 It has been reported that Mori Folium (MF) and Eucommiae Cortex (EC) exhibit pharmacological effects in the treatment of immunosuppression. However, the mechanism of MF and EC against immunosuppression remains unclear.
Jinde Liu +6 more
doaj +1 more source
Quantitative Methods for Optimizing Patient Outcomes in Liver Transplantation [PDF]
arXiv, 2023 Liver transplantation continues to be the gold standard for treating patients with end-stage liver diseases. However, despite the huge success of liver transplantation in improving patient outcomes, long term graft survival continues to be a major problem.
arxiv
Triiodothyronine suppresses humoral immunity but not T-cell-mediated immune response in incubating female eiders (Somateria mollissima) [PDF]
Gen. Comp. Endocrinol. 151 (2007) 188-194, 2007 Immunity is believed to share limited resources with other physiological functions and this may partly account for the fitness costs of reproduction. Previous studies have shown that the acquired immunity of female common eiders (Somateria mollissima) is suppressed during the incubation fast.
arxiv +1 more source
Frontiers in Immunology, 2019 Cancer-associated fibroblasts (CAFs) are prominent components of the microenvironment in most types of solid tumors, and were shown to facilitate cancer progression by supporting tumor cell growth, extracellular matrix remodeling, promoting angiogenesis,
Lea Monteran, Neta Erez
semanticscholar +1 more source
Critical Care, 2021 Background Since the onset of the pandemic, only few studies focused on longitudinal immune monitoring in critically ill COVID-19 patients with acute respiratory distress syndrome (ARDS) whereas their hospital stay may last for several weeks ...
Fabienne Venet +14 more
doaj +1 more source