Results 21 to 30 of about 365,101 (202)
A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma [PDF]
, 2010 Background: The potential anti-cancer effects of mammalian target of rapamycin (mTOR) inhibitors are being intensively studied. To date, however, few randomised clinical trials (RCT) have been performed to demonstrate anti-neoplastic effects in the pure ...Pinna, Antonio D., HIDALGO E, Bechstein, Wolf Otto, M. Heise, Duvoux, Christophe, Heise, Michael, Lerut, Jan, Koert P de Jong, Valente Umberto, Heikki Mäkisalo, Rudolf Steininger, F. Fandrich, SCHMIDT J, Beckebaum, S., Troisi, Roberto I., V. Mazzaferro, Rene Adam, Burra P., Strasser Simone I, Becker, T., Lamby, P.E., Neuhaus Peter, A. Schnitzbauer, Rochon, Justine, Mirza Darius F, Faendrich, Fred, Geissler E. K. ., Fandrich, F., STEININGER R, HEISE M, P. E. Lamby, Rostaing L., Turrion Victor, Chazouilleres, O., VAN HOEK B, Soderdahl G., GRAEB C, Gerd Otto, Georges-Philippe Pageaux, Schlitt H. J., Neville Jamieson, Hans J Schlitt, BURRA P, MAZZAFERRO V, Jong, K.P. de, W. O. Bechstein, Makisalo, H., Rossi, Giorgio, KONIGSRAINER A, Rostaing, Lionel, Soderdahl Gunnar, Rizell, Magnus,, Turrion, V.S., Wolf, P., Strasser, S.I., Jauch, K.W., Philippe Wolf, Mazzaferro V., Wolters H., Pageaux, Georges-Philippe, ZUELKE C, Simone I Strasser, BECKER T, Kneteman N. M., Lerut, Jan P., Johann P Hauss, Duvoux Christophe, Wolters, Heiner, Jamieson N., Zuelke Carl, OTTO G, PINNA AD, Hauss J. P., I. Mutzbauer, Strasser, Simone I, Bilbao, I., Beckebaum Susanne, Schnitzbauer Andreas A, Mutzbauer I., Rizell M., Schmidt, Jan, Koenigsrainer, Alfred, Kneteman, Norman M., WOLTERS H, Lerut Jan P, G.E. Rossi, Gugenheim J., Tim Scholz, K. W. Jauch, N. Jamieson, Wolf O Bechstein, V. Sanchez Turrion, Rossi Giorgio, Andre Roy, van Hoek Bart, COLLEDAN M, Fändrich Fred, Olivier Chazouillères, Roy Andre, RIZELL M, Jan Schmidt, Gugenheim, J., Sanchez Turrion, Victor, K. P. De Jong, Neuhaus, P., R. Troisi, de Jong Koert P, R. Adam, Christophe Duvoux, L. Rostaing, Fandrich, Fred, Graeb, C., Lamby, Philipp E., Philipp E Lamby, Geissler Edward K, NEUHAUS P, A. D. Pinna, J. Pirenne, Pinna, A.D., Schnitzbauer, Andreas, VALENTE U, Pinna Antonio D, Adam Rene, U. Valente, STRASSER SI, Heiner Wolters, Margreiter Raimund, M. Colledan, BILBAO I, Geissler, Edward K., Lerut, Jan P, Chazouillères O., Troisi, Roberto, Heise M., Darius F Mirza, Wolters, H., Antonio D Pinna, M. Rizell, Fändrich F., HAUSS JP, MARGREITER R, O. Chazouilleres, DE JONG KP, Ingrid Mutzbauer, Karl-Walter Jauch, Schlitt, H.J., CHAZOUILLERES O, Victor Sanchez Turrion, Cillo U., Rochon J., Lamby, Philipp E, JAUCH KW, Andreas A Schnitzbauer, Burra, Patrizia, G. Soderdahl, LERUT JP, Mutzbauer, Ingrid, Graeb, Christian, Hauss Johann P, FANDRICH F, Scholz Tim, Strasser S. I., Pinna, Antonio D, BECKEBAUM S, Königsrainer A., Becker, Thomas, Rostaing Lionel, Gunnar Soderdahl, Colledan Michele, MAKISALO H, Roy, A., Makisalo, Heikki, I. Bilbao, U. Cillo, Turrion V. S., Justine Rochon, de Jong, Koert P, Umberto Cillo, Steininger, R., Hoek, Bart van, Gugenheim Jean, G. P. Pageaux, Mutzbauer, I., Geissler, E.K., Kneteman, Norman M, Margreiter, R., Fred Fändrich, Itxarone Bilbao, Edward K Geissler, Pirenne, J., Norman M Kneteman, Colledan M., Chazouilleres, Olivier, Gugenheim, Jean, Carl Zuelke, Magnus Rizell, N. M. Kneteman, Burra, P., Königsrainer Alfred, Bilbao, Itxarone, Otto G., Jacques Pirenne, P. Burra, Mazzaferro, Vincenzo, A. Konigsrainer, Schmidt Jan, E. Hidalgo, Mirza D. F., SODERDAHL G, Mazzaferro Vincenzo, Alfred Königsrainer, Heise, M., Otto Gerd, Margreiter R., Schlitt, Hans J., J. Rochon, Mäkisalo H., Cillo Umberto, Troisi Roberto I, Rossi G., T. Becker, Lamby Philipp E, Zuelke, Carl, ROY A, Scholz T., TURRION VS, Steininger R., Schlitt, Hans J, Schmidt, J., Lamby P. E., Graeb C., Bechstein W. O., Mirza, Darius F, Otto, G., Steininger, Rudolf, Raimund Margreiter, TROISI RI, Adam R., Pirenne, Jacques, Zuelke, C., Jauch K. W., Patrizia Burra, Scholz, Tim, Geissler, Edward K, Königsrainer, Alfred, J. Schimdt, Bechstein, W.O., Hidalgo, E., S. L. Strasser, PAGEAUX GP, Thomas Becker, Hidalgo E., A. Roy, Roy A., Pageaux, G.P., G. Otto, Schnitzbauer, A.A., Umberto Valente, MIRZA DF, Lerut J. P., Mirza, D.F., ADAM R, Colledan, Michele, Mäkisalo Heikki, Ernest Hidalgo, C. Zuelke, Pageaux Georges-Philippe, J. P. Hauss, J. Gugenheim, Roberto I Troisi, Bilbao I., Mazzaferro, V., Otto, Gerd, Cillo, Umberto, WOLF P, Rostaing, L., SCHLITT HJ, Neuhaus P., ROSSI G, Hauss, Johann P., Mutzbauer Ingrid, Vincenzo Mazzaferro, Jamieson, N., Jauch Karl-Walter, Chazouillères Olivier, Schnitzbauer A. A., Adam, R., Schmidt J., Strasser, Simone I., Bechstein Wolf O, Wolf Philippe, P. Neuhaus, C. Duvoux, Pirenne Jacques, Hauss, Johann P, Becker Thomas, D. F. Mirza, Bilbao Itxarone, Valente, U., P. Wolf, Bart van Hoek, Duvoux, C., T. Scholz, Jamieson, Neville, ROCHON J, Jan P Lerut, Pageaux G. P., Scholz, T., Lionel Rostaing, Schnitzbauer, Andreas A, MUTZBAUER I, Lerut, J.P., Rizell, Magnus, H. Wolters, Bechstein, Wolf O., Steininger Rudolf, BECHSTEIN WO, R. Steininger, B. Van Hoek, Konigsrainer, A., Becker T., Wolters Heiner, de Jong, Koert P., Roy, Andre, Kneteman Norman M, Bechstein, Wolf O, Troisi, Roberto I, Schnitzbauer, Andreas A., Schlitt Hans J, J. P. Lerut, PINNA, ANTONIO DANIELE, Burra Patrizia, SCHOLZ T, Wolf P., Christian Graeb, PIRENNE J, Beckebaum, Susanne, Rochon Justine, DUVOUX C, Adam, Rene, van Hoek B., Margreiter, Raimund, van Hoek, Bart, LAMBY PE, Jamieson Neville, S. Beckebaum, Pirenne J., Hidalgo Ernest, Soderdahl, Gunnar, GUGENHEIM J, Rochon, J., Jean Gugenheim, Giorgio Rossi, Hauss, J.P., Duvoux C., KNETEMAN NM, C. Graeb, Turrion, Victor Sanchez, Rizell, M., H. J. Schlitt, CILLO U, GEISSLER EK, SCHNITZBAUER AA, JAMIESON N, Jauch, Karl-Walter, H. Makisalo, Beckebaum S., Peter Neuhaus, R. Margreiter, Rizell Magnus, Kneteman, N.M., Mirza, Darius F., E. K. Geissler, Rossi, G., Heise Michael, Michael Heise, Hoek, B. van, Hidalgo, Ernest, Michele Colledan, Wolf, Philippe, Troisi R. I., Zuelke C., Valente, Umberto, Neuhaus, Peter, Valente U., Soderdahl, G., ROSTAING L, de Jong K. P., Cillo, U., Graeb Christian, Susanne Beckebaum, Troisi, R.I., Colledan, M., Duvoux, C, Kneteman, NM, Schnitzbauer, AA, Rochon, J, Graeb, C, Adam, R, Bilbao, I, Zuelke, C, Burra, P, de, Jong KP +402 morecore +4 more sourcesInitial immunosuppression used.
, 2022 Initial immunosuppression used.Joshua Storrar (10682937), Francesco Rainone (13955728), Rajkumar Chinnadurai (7532972), Dimitrios Poulikakos (6672590), Smeeta Sinha (4847929), Philip A. Kalra (7670933), Constantina Chrysochou (4096549), Elizabeth Lamerton (6727274), James Ritchie (4096552), Tarra Gill-Taylor (13955725) +9 morecore +1 more sourceMonocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes
Critical Care, 2020 Background Decreased monocytic (m)HLA-DR expression is the most studied biomarker of sepsis-induced immunosuppression. To date, little is known about the relationship between sepsis characteristics, such as the site of infection, causative pathogen, or ...Guus P. Leijte, Thomas Rimmelé, Matthijs Kox, Niklas Bruse, Céline Monard, Morgane Gossez, Guillaume Monneret, Peter Pickkers, Fabienne Venet +8 moredoaj +1 more sourceMonocyte Trajectories Endotypes Are Associated With Worsening in Septic Patients
Frontiers in Immunology, 2021 Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. The immune system plays a key role in sepsis onset and remains dysregulated over time in a heterogeneous manner.Maxime Bodinier, Estelle Peronnet, Karen Brengel-Pesce, Filippo Conti, Thomas Rimmelé, Julien Textoris, Christophe Vedrine, Laurence Quemeneur, Andrew D. Griffiths, Lionel K. Tan, Fabienne Venet, Fabienne Venet, Delphine Maucort-Boulch, Delphine Maucort-Boulch, Delphine Maucort-Boulch, Guillaume Monneret, the REALISM study group +16 moredoaj +1 more sourceTo be (immunosuppressive) or not to be [PDF]
Nature Reviews Cancer, 2019 Singhal et al. characterized tumour-infiltrating monocyte and macrophage lineage cells in patients with early stage lung cancer and found that, contrary to data in mouse models, the function of these cells might not be primarily immunosuppressive.openaire +2 more sourcesA 9-mRNA signature measured from whole blood by a prototype PCR panel predicts 28-day mortality upon admission of critically ill COVID-19 patients
Frontiers in Immunology, 2022 Immune responses affiliated with COVID-19 severity have been characterized and associated with deleterious outcomes. These approaches were mainly based on research tools not usable in routine clinical practice at the bedside. We observed that a multiplex Claire Tardiveau, Claire Tardiveau, Guillaume Monneret, Guillaume Monneret, Anne-Claire Lukaszewicz, Anne-Claire Lukaszewicz, Valérie Cheynet, Valérie Cheynet, Elisabeth Cerrato, Elisabeth Cerrato, Katia Imhoff, Katia Imhoff, Estelle Peronnet, Estelle Peronnet, Maxime Bodinier, Maxime Bodinier, Louis Kreitmann, Louis Kreitmann, Sophie Blein, Sophie Blein, Jean-François Llitjos, Jean-François Llitjos, Jean-François Llitjos, Filippo Conti, Filippo Conti, Morgane Gossez, Morgane Gossez, Marielle Buisson, Hodane Yonis, Martin Cour, Laurent Argaud, Marie-Charlotte Delignette, Florent Wallet, Frederic Dailler, Céline Monard, Karen Brengel-Pesce, Karen Brengel-Pesce, Fabienne Venet, Fabienne Venet, the RICO study group +39 moredoaj +1 more sourceTranscriptome modulation by hydrocortisone in severe burn shock: ancillary analysis of a prospective randomized trial
Critical Care, 2017 Background Despite shortening vasopressor use in shock, hydrocortisone administration remains controversial, with potential harm to the immune system. Few studies have assessed the impact of hydrocortisone on the transcriptional response in shock, and we Jonathan Plassais, Fabienne Venet, Marie-Angélique Cazalis, Diane Le Quang, Alexandre Pachot, Guillaume Monneret, Sylvie Tissot, Julien Textoris +7 moredoaj +1 more sourceEarly herpes and TTV DNAemia in septic shock patients: a pilot study
Intensive Care Medicine Experimental, 2019 Background Septic shock patients exhibit an increased incidence of viral reactivation. Precise timing of such reactivation—as an early marker of immune suppression, or as a consequence of the later—is not known precisely.François Mallet, Magali Perret, Trang Tran, Boris Meunier, Audrey Guichard, Olivier Tabone, Marine Mommert, Karen Brengel-Pesce, Fabienne Venet, Alexandre Pachot, Guillaume Monneret, Frederic Reynier, Christophe Védrine, Philippe Leissner, Virginie Moucadel, Alain Lepape, Julien Textoris, MIPrea group, REALISM group +18 moredoaj +1 more sourceT cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19
EBioMedicine, 2022 Summary: Background: In critically ill COVID-19 patients, the initial response to SARS-CoV-2 infection is characterized by major immune dysfunctions.Fabienne Venet, Morgane Gossez, Frank Bidar, Maxime Bodinier, Rémy Coudereau, Anne-Claire Lukaszewicz, Claire Tardiveau, Karen Brengel-Pesce, Valérie Cheynet, Marie-Angélique Cazalis, Rémi Pescarmona, Lorna Garnier, Marine Ortillon, Marielle Buisson, Maude Bouscambert-Duchamp, Florence Morfin-Sherpa, Jean-Sébastien Casalegno, Filippo Conti, Thomas Rimmelé, Laurent Argaud, Martin Cour, Mitra Saadatian-Elahi, Laetitia Henaff, Philippe Vanhems, Guillaume Monneret +24 moredoaj +1 more source
