Results 31 to 40 of about 365,101 (202)

A nongenomic mechanism for progesterone-mediated immunosuppression: Inhibition of K+ channels, Ca2+ signaling, and gene expression in T lymphocytes [PDF]

, 1998
The mechanism by which progesterone causes localized suppression of the immune response during pregnancy has remained elusive. Using human T lymphocytes and T cell lines, we show that progesterone, at concentrations found in the placenta, rapidly and ...
Christopher M. Fanger, Khoury, Rosana M, Negulescu, Paul A, Cahalan, Michael D, Neben, Amber L, Hubert H. Kerschbaum, Fanger, Christopher M, Rosana M. Khoury, Kerschbaum, Hubert H, Claudia Eder, Amber L. Neben, George R. Ehring, Eder, Claudia, Michael D. Cahalan, Paul A. Negulescu, Ehring, George R, Negulescu, PA, Fanger, CM, Kerschbaum, HH, Khoury, RM, Ehring, GR, Eder, C, Cahalan, MD, Neben, AL   +23 more
core   +1 more source

Endogenous Retroviruses Transcriptional Modulation After Severe Infection, Trauma and Burn

Frontiers in Immunology, 2019
Although human endogenous retroviruses (HERVs) expression is a growing subject of interest, no study focused before on specific endogenous retroviruses loci activation in severely injured patients.
Olivier Tabone, Marine Mommert, Marine Mommert, Camille Jourdan, Elisabeth Cerrato, Matthieu Legrand, Alain Lepape, Bernard Allaouchiche, Bernard Allaouchiche, Thomas Rimmelé, Alexandre Pachot, Guillaume Monneret, Guillaume Monneret, Fabienne Venet, Fabienne Venet, François Mallet, François Mallet, Julien Textoris, Julien Textoris   +18 more
doaj   +1 more source

Effect of Maintaining Immunosuppression After Kidney Allograft Failure on Mortality and Retransplantation

Transplantation Direct, 2023
Background. Few studies have addressed immunosuppression management after allograft failure (AF). Immunosuppression withdrawal to minimize complications must be balanced with the risk of sensitization and potentially reduced retransplantation.
Suryanarayanan Balakrishnan, MD, Byron Smith, PhD, MS, Andrew Bentall, MD, Aleksandra Kukla, MD, Massini Merzkani, MD, Mark Stegall, MD, Carrie Schinstock, MD   +6 more
doaj   +1 more source

Mesenchymal stem cell-mediated T cell immunosuppression [PDF]

, 2017
Besides being a pool forstromal cells and connective tissues, the mesenchymal stem cells (MSCs) as well exert a potent immunosuppression against almost all types of immune cells, particularly T cells.
Al-Graittee, Satar Jabbar Rahi, Ramasamy, Rajesh, Lawal, Hamza   +2 more
core   +1 more source

The Mechanism of Mori Folium and Eucommiae Cortex against Cyclophosphamide-Induced Immunosuppression Integrating Network Pharmacology, Molecular Docking, Molecular Dynamics Simulations, and Experimental Validation

Metabolites, 2023
It has been reported that Mori Folium (MF) and Eucommiae Cortex (EC) exhibit pharmacological effects in the treatment of immunosuppression. However, the mechanism of MF and EC against immunosuppression remains unclear.
Jinde Liu, Qiao Rong, Chunxiao Zhang, Ali Tariq, Lin Li, Yongning Wu, Feifei Sun   +6 more
doaj   +1 more source

Immunosuppression.

, 2019
Immunosuppression.
Thomas Rath (468079), Irena Kroeger (7406549), Oliver Witzke (117125), Robert Schuhmann (7406546), Oliver Vonend (7406543), Bianca Zukunft (4678456), Anja Mühlfeld (5467574), Claudia Sommerer (3153246), Martina Porstner (5467568), Susanne Brakemeier (4344538), Wolfgang Arns (5467571), Frank Lehner (360876), Klemens Budde (4344541)   +12 more
core   +1 more source

LTR-retrotransposon transcriptome modulation in response to endotoxin-induced stress in PBMCs

BMC Genomics, 2018
Background Human Endogenous Retroviruses (HERVs) and Mammalian apparent LTR-retrotransposons (MaLRs) represent the 8% of our genome and are distributed among our 46 chromosomes.
Marine Mommert, Olivier Tabone, Guy Oriol, Elisabeth Cerrato, Audrey Guichard, Magali Naville, Paola Fournier, Jean-Nicolas Volff, Alexandre Pachot, Guillaume Monneret, Fabienne Venet, Karen Brengel-Pesce, Julien Textoris, François Mallet   +13 more
doaj   +1 more source

Longitudinal assessment of IFN-I activity and immune profile in critically ill COVID-19 patients with acute respiratory distress syndrome

Critical Care, 2021
Background Since the onset of the pandemic, only few studies focused on longitudinal immune monitoring in critically ill COVID-19 patients with acute respiratory distress syndrome (ARDS) whereas their hospital stay may last for several weeks ...
Fabienne Venet, Martin Cour, Thomas Rimmelé, Sebastien Viel, Hodane Yonis, Remy Coudereau, Camille Amaz, Paul Abraham, Céline Monard, Jean-Sebastien Casalegno, Karen Brengel-Pesce, Anne-Claire Lukaszewicz, Laurent Argaud, Guillaume Monneret, the RICO study group   +14 more
doaj   +1 more source

Induction immunosuppression and post-transplant diabetes mellitus: a propensity-matched cohort study

Frontiers in Endocrinology, 2023
IntroductionPost-transplant diabetes mellitus (PTDM) is a common complication among cardiac transplant recipients, causing diabetes-related complications and death.
Suruchi K. Gupta, Suruchi K. Gupta, Suruchi K. Gupta, Elizabeth Mostofsky, Shweta R. Motiwala, Shweta R. Motiwala, Ali Hage, Ali Hage, Murray A. Mittleman, Murray A. Mittleman, Murray A. Mittleman   +10 more
doaj   +1 more source

Advances in the understanding and treatment of sepsis-induced immunosuppression

, 2017
International audienceSepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated host response to infection. Sepsis can induce acute kidney injury and multiple organ failures and represents the most common cause of death ...
Fabienne Venet, Guillaume Monneret, Venet, Fabienne, Monneret, Guillaume   +3 more
core   +1 more source