Results 31 to 40 of about 458,490 (361)

Intestinal transplantation in children under FK 506 immunosuppression [PDF]

, 1993
Intestinal transplantation, solitary (n = 3) or in combination with the liver (n = 7), was performed in 10 pediatric patients with intestinal failure. The liver was only replaced if there was liver failure and portal hypertension.
Adrian Casavilla, Andreas G. Tzakis, Anthony J. Demetris, Bakr Nour, David H. Van Thiel, Eduardo Yunis, Goulet, Grant, Iwaki, Jorge Reyes, Kareem Abu-Elmagd, Murase, Murase, Rick Selby, Samuel Kocoshis, Satoru Todo, Schraut, Shaffer, Starzl, Starzl, Starzl, Thomas E. Starzl, Todo, Todo, Tzakis, Tzakis, Zhong   +26 more
core   +1 more source

Early herpes and TTV DNAemia in septic shock patients: a pilot study

Intensive Care Medicine Experimental, 2019
Background Septic shock patients exhibit an increased incidence of viral reactivation. Precise timing of such reactivation—as an early marker of immune suppression, or as a consequence of the later—is not known precisely.
François Mallet, Magali Perret, Trang Tran, Boris Meunier, Audrey Guichard, Olivier Tabone, Marine Mommert, Karen Brengel-Pesce, Fabienne Venet, Alexandre Pachot, Guillaume Monneret, Frederic Reynier, Christophe Védrine, Philippe Leissner, Virginie Moucadel, Alain Lepape, Julien Textoris, MIPrea group, REALISM group   +18 more
doaj   +1 more source

Generic immunosuppressants

Pediatric Nephrology, 2017
Immunosuppressive drugs for solid organ transplantation are critical dose drugs with a narrow therapeutic index. Many of the most commonly used innovator drugs are off patent and have been replicated by generic counterparts, often at substantial cost-savings to the patient.
Mara Medeiros, Julia Lumini, Noah Stern, Gilberto Castañeda-Hernández, Guido Filler   +4 more
openaire   +5 more sources

Understanding sepsis-induced immunosuppression and organ dysfunctions: from immunosuppression to immunotherapy

Exploration of Immunology, 2022
Sepsis is a life-threatening condition caused by dysregulated host immune response to infection, leading to persistent inflammation followed by immunosuppression.
Dablu Lal Gupta, Tejprakash Sinha, Richa Pathak, Sanjeev Bhoi, D. N. Rao   +4 more
doaj   +1 more source

Current status of intestinal transplantation in children [PDF]

, 1998
Purpose: A clinical trial of intestinal transplantation (Itx) under tacrolimus and prednisone immunosuppression was initiated in June 1990 in children with irreversible intestinal failure and who were dependent on total parenteral nutrition (TPN ...
Asfar, Billingham, Casavilla, Deltz, Edward M Barksdale, Fontes, Furukawa, Garau, Goulet, Grant, Grant, Grant, Green, Hiro Furukawa, Iwaki, Javier Bueno, John J Fung, Jorge Reyes, Kareem Abu-Elmagd, Kashiwagi, Langnas, Lee, Lillehei, Manez, Margreiter, McAlister, Mike Green, Monchik, Murase, Murase, Porter, Putnam, Randhawa, Rao, Reyes, Reyes, Reyes, Samuel Kocoshis, Satoru Todo, Sharon Strom, Sigurdsson, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Takaya, Thomas E Starzl, Todo, Tzakis, White, William Irish   +52 more
core   +1 more source

Endogenous Retroviruses Transcriptional Modulation After Severe Infection, Trauma and Burn

Frontiers in Immunology, 2019
Although human endogenous retroviruses (HERVs) expression is a growing subject of interest, no study focused before on specific endogenous retroviruses loci activation in severely injured patients.
Olivier Tabone, Marine Mommert, Marine Mommert, Camille Jourdan, Elisabeth Cerrato, Matthieu Legrand, Alain Lepape, Bernard Allaouchiche, Bernard Allaouchiche, Thomas Rimmelé, Alexandre Pachot, Guillaume Monneret, Guillaume Monneret, Fabienne Venet, Fabienne Venet, François Mallet, François Mallet, Julien Textoris, Julien Textoris   +18 more
doaj   +1 more source

Effect of Maintaining Immunosuppression After Kidney Allograft Failure on Mortality and Retransplantation

Transplantation Direct, 2023
Background. Few studies have addressed immunosuppression management after allograft failure (AF). Immunosuppression withdrawal to minimize complications must be balanced with the risk of sensitization and potentially reduced retransplantation.
Suryanarayanan Balakrishnan, MD, Byron Smith, PhD, MS, Andrew Bentall, MD, Aleksandra Kukla, MD, Massini Merzkani, MD, Mark Stegall, MD, Carrie Schinstock, MD   +6 more
doaj   +1 more source

The Mechanism of Mori Folium and Eucommiae Cortex against Cyclophosphamide-Induced Immunosuppression Integrating Network Pharmacology, Molecular Docking, Molecular Dynamics Simulations, and Experimental Validation

Metabolites, 2023
It has been reported that Mori Folium (MF) and Eucommiae Cortex (EC) exhibit pharmacological effects in the treatment of immunosuppression. However, the mechanism of MF and EC against immunosuppression remains unclear.
Jinde Liu, Qiao Rong, Chunxiao Zhang, Ali Tariq, Lin Li, Yongning Wu, Feifei Sun   +6 more
doaj   +1 more source

Immunosuppressive Medications [PDF]

Clinical Journal of the American Society of Nephrology, 2016
Immunosuppressive agents are commonly used in the nephrologist's practice in the treatment of autoimmune and immune-mediated diseases and transplantation, and they are investigational in the treatment of AKI and ESRD. Drug development has been rapid over the past decades as mechanisms of the immune response have been better defined both by serendipity (
openaire   +2 more sources

T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19

EBioMedicine, 2022
Summary: Background: In critically ill COVID-19 patients, the initial response to SARS-CoV-2 infection is characterized by major immune dysfunctions.
Fabienne Venet, Morgane Gossez, Frank Bidar, Maxime Bodinier, Rémy Coudereau, Anne-Claire Lukaszewicz, Claire Tardiveau, Karen Brengel-Pesce, Valérie Cheynet, Marie-Angélique Cazalis, Rémi Pescarmona, Lorna Garnier, Marine Ortillon, Marielle Buisson, Maude Bouscambert-Duchamp, Florence Morfin-Sherpa, Jean-Sébastien Casalegno, Filippo Conti, Thomas Rimmelé, Laurent Argaud, Martin Cour, Mitra Saadatian-Elahi, Laetitia Henaff, Philippe Vanhems, Guillaume Monneret   +24 more
doaj   +1 more source