Results 91 to 100 of about 290,024 (350)

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

The impact of pharmacists’ interventions within the closed loop immunosuppressant management process on kidney transplant recipients: a retrospective cohort study

Frontiers in Immunology
IntroductionNowadays, kidney transplant recipients’ primary challenge is improving graft function. However, they are rarely provided effective long-term instructions on immunosuppressant use after transplant.
Hongxia Chen, Chuan Li, Shengsong Ou, Xiaoyu Chen   +3 more
doaj   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Posttransplant lymphoproliferative disorders in adult and pediatric renal transplant patients receiving tacrolimus-based immunosuppression [PDF]

, 1999
Between March 27, 1989 and December 31, 1997, 1316 kidney transplantations alone were performed under tacrolimus-based immunosuppression at our center.
Ellis, D, Fedorek, S, Fung, JJ, Hakala, TR, Jain, A, Johnston, J, Jordan, ML, Lombardozzi-Lane, S, McCauley, J, Nalesnik, M, Randhawa, P, Scantlebury, VP, Shapiro, R, Simmons, RL, Starzl, TE, Vivas, C   +15 more
core   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Immunosuppressive Therapy [PDF]

Postgraduate Medical Journal, 1981
  +5 more sources

Perinatal Management of Neuromyelitis Optica Spectrum Disorder in Pregnancy: A Case Report

International Journal of Women's Health
Jue Wang, Rong Hu, Hao Zhu Department of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, People’s Republic of ChinaCorrespondence: Hao Zhu, Department of Obstetrics, the Obstetrics and Gynecology Hospital of Fudan University,
Wang J, Hu R, Zhu H
doaj  

Living donor liver transplantation for autoimmune hepatitis in identical monozygotic twins: a case report

Clinical Transplantation and Research
Liver transplantation (LT) is an effective treatment for end-stage liver diseases, including autoimmune hepatitis. Advances in immunosuppressive therapy have improved patient and graft survival; however, these treatments can cause serious side effects ...
Kulbhushan Haldeniya, Kausar Makki, Yogesh Yadav, Tathagata Karan, Nalini Kanta Ghosh, Piyush Srivastava, Anil Agarwal, Vivek Vij   +7 more
doaj   +1 more source

Successful rescue of fulminant myocarditis with mechanical circulatory support and immunosuppression therapy: A case report. [PDF]

Front Cardiovasc Med, 2023
Zhou C.
europepmc   +1 more source