Cadaveric renal transplantation under cyclosporine-steroid therapy [PDF]
Ninety-seven cadaveric renal transplants were performed upon 96 patients during 1981. The one year patient mortality was 2.1 per cent. Seventy of the recipients were undergoing trasplantation for the first time.
Hakala, TR+4 more
core
In silico tumor control induced via alternating immunostimulating and immunosuppressive phases [PDF]
Despite recent advances in the field of Oncoimmunology, the success potential of immunomodulatory therapies against cancer remains to be elucidated. One of the reasons is the lack of understanding on the complex interplay between tumor growth dynamics and the associated immune system responses.
arxiv
Experience with posttransplant lymphoproliferative disorders in solid organ transplant recipients [PDF]
Nearly 6000 solid organ transplants have been performed at the University of Pittsburgh since 1981. Posttransplant lymphoproliferative disorders (PTLD) have occurred in 131 patients, at a frequency of 2.2%.
Cooper, M+6 more
core
A prospective randomized trial of FK506-based immunosuppression after renal transplantation [PDF]
A group of 204 adult patients was entered into a prospective, randomized trial comparing FK506/pred-nisone with FK506/azathioprine/prednisone after renal transplantation between August 1, 1991 and October 11,1992.
Demetris, AJ+12 more
core +1 more source
Large granular lymphocytic leukemia (LGL) is a rare lymphoproliferative disorder that involves the T-cell lineage in around 85% of cases and NK-cell lineage in 15%.
Tendai Kwaramba+5 more
doaj
La terapia immunosoppressiva nel trapianto di rene
Immunosuppressive therapy in renal transplantation can be distinguished in induction therapy and maintenance therapy. Induction therapy is an intense immunosuppressive therapy administered at the time of kidney transplantation to reduce the risk of acute
Aris Tsalouchos, Maurizio Salvadori
doaj +1 more source
Hepatitis C virus genotypes in liver transplant recipients: Impact on posttransplant recurrence, infections, response to interferon-α therapy and outcome [PDF]
Background. End-stage liver disease due to hepatitis C virus (HCV) is the most common indication for liver transplantation in U.S. veterans. We investigated the influence of HCV genotypes on the incidence and timing of recurrent HCV hepatitis, survival ...
Fung, JJ+10 more
core +1 more source
Survival predictors in paraquat intoxification and role of immunosuppression
Paraquat poisoning resulted in multiorgan failure and is associated with high mortality. We audited 83 historical cases of paraquat poisoning in past 2 years treated with conventional decontamination and supportive treatment, followed by enrolling 85 ...
Keng-Hee Koh+10 more
doaj +1 more source
Whole Exome Sequencing to Estimate Alloreactivity Potential Between Donors and Recipients in Stem Cell Transplantation [PDF]
Whole exome sequencing was performed on HLA-matched stem cell donors and transplant recipients to measure sequence variation contributing to minor histocompatibility antigen differences between the two. A large number of nonsynonymous single nucleotide polymorphisms were identified in each of the nine unique donor-recipient pairs tested. This variation
arxiv
CD4 counts and the risk of systemic non-Hodgkin’s lymphoma in individuals with HIV in the UK
Since the introduction of highly active antiretroviral therapy, there has been a decline in the incidence of non-Hodgkin’s lymphoma among HIV-infected individuals.
Mark Bower+19 more
doaj +1 more source