Current status of intestinal transplantation in children [PDF]
Purpose: A clinical trial of intestinal transplantation (Itx) under tacrolimus and prednisone immunosuppression was initiated in June 1990 in children with irreversible intestinal failure and who were dependent on total parenteral nutrition (TPN ...
Asfar+52 more
core +1 more source
Perforator propeller flap for coverage of Achilles region defects caused by pyoderma gangrenosum
: Pyoderma gangrenosum (PG) is a rare neutrophilic inflammatory skin disease. Systemic corticosteroid and immunosuppressive agents are the mainstay treatment. PG usually precludes a surgical approach due to pathergy phenomenon.
Chun Wa Fong+6 more
doaj
Challenges in constructing genetic instruments for pharmacologic therapies [PDF]
The genes that encode the targets of most therapies do not have rare variants with large-effect or common variants with moderate effects on the biomarker reflecting the pharmacologic action of the corresponding therapy. Therefore, providing genetic target validation for most therapies is challenging.
arxiv
Successful rescue of fulminant myocarditis with mechanical circulatory support and immunosuppression therapy: A case report. [PDF]
Zhou C.
europepmc +1 more source
Pneumocystis and Herpesviruses in Immunocompromised Children [PDF]
Objective. Objectives. Study of the role of herpes viruses and pathogen in the etiology of infectious diseases in children with immunosuppression of different nature to provide an adequate etiotropic therapy and prophylaxis of these infections ...
Savinkov P.A.+10 more
doaj
Immunosuppression Therapy in Acquired Hemophilia A: Pursuing an Optimal Regimen. [PDF]
Teixeira Passos D+4 more
europepmc +1 more source
Tumor Associated Neutrophils. Their Role in Tumorigenesis, Metastasis, Prognosis and Therapy
Tumor Associated Neutrophils (TANs) are engaged into the tumor microenvironment by cytokines and chemokines, can be distinguished according to their activation and cytokine status and effects on tumor cell growing in N1 and N2 TANs.
M. Masucci, M. Minopoli, M. Carriero
semanticscholar +1 more source
Questing for an optimal, universal viral agent for oncolytic virotherapy [PDF]
One of the most promising strategies to treat cancer is attacking it with viruses designed to exploit specific altered pathways. Here, the effects of oncolytic virotherapy on tumors having compact, papillary and disconnected morphologies are investigated through computer simulations of a multiscale model coupling macroscopic reaction diffusion ...
arxiv
Humoral Response After SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Role of Immunosuppression Therapy. [PDF]
López V+6 more
europepmc +1 more source
There is growing evidence that mesenchymal stem cell (MSC)-based immunosuppression was mainly attributed to the effects of MSC-derived extracellular vesicles (MSC-EVs).
C. Harrell+4 more
semanticscholar +1 more source