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Personalized approaches to active immunotherapy in cancer
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2016Immunotherapy is emerging as a promising anti-cancer curative modality. However, in contrast to recent advances obtained employing checkpoint blockade agents and T cell therapies, clinical efficacy of therapeutic cancer vaccines is still limited. Most vaccination attempts in the clinic represent "off-the shelf" approaches since they target common "self"
Ophir E +4 more
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1976
When we started the first clinical controlled trial or active immunotherapy in 1963 (MATHS et al., 1968, 1969a), the favourable tumour growth plate of the immune balance was not known. Nevertheless, it appeared reasonable to conduct experiments on active immunotherapy of experimental established tumours, and to apply them to man in the conditions and ...
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When we started the first clinical controlled trial or active immunotherapy in 1963 (MATHS et al., 1968, 1969a), the favourable tumour growth plate of the immune balance was not known. Nevertheless, it appeared reasonable to conduct experiments on active immunotherapy of experimental established tumours, and to apply them to man in the conditions and ...
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Active Specific Immunotherapy in Colon Cancer
2005Colorectal cancer is one of the leading causes of cancer-related mortality. After a series of clinical trials, the adjuvant 5-FU-based chemotherapy has established a definitive role in the management of stage III colon cancer. While the precise role for chemotherapy in stage II disease remains under investigation, less toxic treatment modalities such ...
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Genetic Vaccination for the Active Immunotherapy of Cancer
Current Gene Therapy, 2001Molecular biology techniques have given novel impetus to the immunotherapy of cancer because they have catalyzed the identification of several potential tumor antigens, and permitted the generation of vectors for the delivery of genetic material encoding these antigens.
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Inflammasome-Activating Nanovaccine for Cancer Immunotherapy
Cancer ResearchA range of advanced nanovaccines (NV) combined with immunotherapies has recently emerged for treating malignant tumors and has demonstrated promising tumor-suppressive effects. Nevertheless, their effectiveness is often limited by immunosuppression within the tumor microenvironment.
Wenyao Zhen, Xiaoyuan Chen
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Active Tumor Immunotherapy with BCG
SOUTHERN MEDICAL JOURNAL, 1973E, Rosenberg, R, Powell
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Clinical trials of immunotherapy: Active immunotherapy or therapeutic vaccination
1999During the recent years, new information obtained from basic immunology and from the use of molecular techniques has advanced our understanding of mechanism of induction of immune response and caused a new wave of studies of active immunotherapy of cancer both at pre-clinical and clincal level.
Maio M, Parmiani G
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Modeling Active Colloids: From Active Brownian Particles to Hydrodynamic and Chemical Fields
Annual Review of Condensed Matter Physics, 2023Andreas Zottl, Holger Stark
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