Results 201 to 210 of about 44,698 (259)
Editorial: Overcoming resistance to immune checkpoint inhibitors: mechanisms and strategies in cancer therapy. [PDF]
Piccinelli M +4 more
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Current Opinion in Oncology, 1997
Some of the most dramatic advances in the treatment of cancer have used the immune system in combination with conventional or transplantation chemotherapy. Adoptive immunotherapy has been used for relapses after allogeneic bone marrow transplantation, and it has been particularly effective for chronic myeloid leukemia.
K, Ballen, F M, Stewart
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Some of the most dramatic advances in the treatment of cancer have used the immune system in combination with conventional or transplantation chemotherapy. Adoptive immunotherapy has been used for relapses after allogeneic bone marrow transplantation, and it has been particularly effective for chronic myeloid leukemia.
K, Ballen, F M, Stewart
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Adoptive immunotherapy for cancer
Immunological Reviews, 2013SummaryRecent clinical success has underscored the potential for immunotherapy based on the adoptive cell transfer (ACT) of engineered T lymphocytes to mediate dramatic, potent, and durable clinical responses. This success has led to the broader evaluation of engineered T‐lymphocyte‐based adoptive cell therapy to treat a broad range of malignancies. In
Marco, Ruella, Michael, Kalos
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Chemo-immunotherapy and chemo-adoptive immunotherapy of cancer
Cancer Treatment Reviews, 2001The chemo-immunotherapy (CIT) and chemo-adoptive immunotherapy (CAIT) regimens tested in the past decade are summarized. From them we have learned a great deal about the interactions between various chemotherapeutic agents, immune modulating agents and effector cells.
G G, Gomez, R B, Hutchison, C A, Kruse
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Adoptive Immunotherapy for Malignant Glioma
The Cancer Journal, 2003Despite remarkable advancements in imaging modalities and treatment options available to patients diagnosed with malignant brain tumors, the prognosis for those with high-grade lesions remains poor. The imprecise mechanisms of currently available treatments to manage these tumors do not spare damage to the normal surrounding brain and often result in ...
Duane A, Mitchell +2 more
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Mononuclear Cell Adoptive Immunotherapy
Hematology/Oncology Clinics of North America, 1994In contrast with red cells, platelets, and granulocytes, hemotherapy using lymphocytes and monocytes is only beginning to be explored. Blood banks and transfusion services, the traditional sources of expertise in sterile cell processing, storage, and transfusion, have played an integral role in the early technical development of mononuclear cell ...
J H, Lee, H G, Klein
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Enhancing adoptive immunotherapy of cancer
Expert Opinion on Biological Therapy, 2010Conventional therapies, including surgery, chemotherapy and radiotherapy have contributed much to cancer treatment. However, these treatment modalities fail in a large proportion of patients, and there is a great need for effective alternate therapies.
Jennifer A, Westwood +6 more
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Adoptive immunotherapy of HCMV infection
Cytotherapy, 2007Human cytomegalovirus (HCMV) infection or reactivation is a frequent cause of morbidity and mortality in immunocompromised individuals such as transplant recipients. Primary HCMV infection or reactivation of HCMV from latency is mostly asymptomatic in immunocompetent individuals and is controlled by the host's cell-mediated immune response.
M, Kapp +3 more
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Costimulatory approaches to adoptive immunotherapy
Current Opinion in Oncology, 1998Costimulation is critical for induction of full T-cell effector function, and thus represents an attractive immunotherapeutic approach for the treatment of cancer. This review examines these approaches, including ex vivo T-cell expansion, systemic "delivery" of constimulation, tumors transduced or transfected with costimulatory ligands, and vaccine ...
D N, Liebowitz, K P, Lee, C H, June
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Adoptive immunotherapy against sarcomas
Expert Opinion on Biological Therapy, 2014Conventional treatments reached an unsatisfactory therapeutic plateau in the treatment of advanced unresectable bone and soft tissue sarcomas that remain an unsolved medical need. Several evidences support the concept that adoptive immunotherapy may effectively integrate within the complex and multidisciplinary treatment of sarcomas.In this work we ...
Mesiano, Giulia +11 more
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