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Adoptive Immunotherapy of Ovarian Carcinoma
Gynecologic Oncology, 2002info:eu-repo/semantics ...
de Gramont, Aimery +5 more
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Adoptive immunotherapy of urologic tumors
1989The treatment of humans with advanced cancer represents a major therapeutic challenge. One approach to treating metastatic cancer is immunotherapy, which can be classified into active and passive categories. Active immunotherapy refers to the immunization of the tumor-bearing host with materials that attempt to induce in the host a state of immune ...
A, Belldegrun, S A, Rosenberg
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Adoptive Immunotherapy of Advanced Melanoma
Current Treatment Options in Oncology, 2012Adoptive cell therapy (ACT) has emerged as an effective therapy for patients with metastatic melanoma. Since the first introduction of the protocol in 1988 [1], major improvements have been achieved with response rates of 40%-72% among patients who were resistant to previous treatment lines.
Ronnie, Shapira-Frommer +1 more
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Technological advances in adoptive immunotherapy
Drugs of Today, 2005Adoptive immunotherapy is an attractive and elegant strategy for treating a variety of life-threatening diseases. Several approaches have been developed to generate antigen-specific CD4+ and CD8+ T cells for adoptive T-cell therapy in cancer and infectious diseases.
Mathias, Oelke +2 more
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Adoptive Immunotherapy for Hodgkin's Lymphoma
International Journal of Hematology, 2006Adoptive transfer of tumor-specific T-cells is an attractive strategy for the treatment of patients with refractory or relapsed Hodgkin's lymphoma. However, Hodgkin's lymphomas possess a range of tumor-evasion mechanisms, which must be overcome before the full potential of immunotherapies can be achieved.
Alana A, Kennedy-Nasser +2 more
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An artificial solution for adoptive immunotherapy
Trends in Biotechnology, 2003Abstract Adoptive immunotherapy is a promising strategy in the battle against cancer and infectious diseases and the recently developed artificial antigen-presenting cell (aAPC) overcomes several obstacles for this therapy. The aAPC recapitulates the natural in vivo antigen-presenting cell (APC)–T cell interactions by coupling human leukocyte ...
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CASE FOR ADOPTIVE IMMUNOTHERAPY IN CANCER
The Lancet, 1982Patients with normal immune systems may be unable to mount effective defences against solid tumours because of (1) the generation of suppressor T cells in the low zone tolerance response elicited by the low concentrations of antigen furnished by slow growing solid tumours; (2) the ineffectiveness of the cytolytic T-cell response when the tumour cell ...
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