Results 211 to 220 of about 119,989 (312)

Boron in My Mind: A Comprehensive Review of the Evolution of the Diverse Syntheses of 4‐Borono‐l‐Phenylalanine, the Leading Agent for Boron Neutron Capture Therapy

ChemMedChem, EarlyView.
Boron Neutron Capture Therapy is a promising technique for treating “untreatable” brain cancers by having 10B nuclei absorb neutrons and then decay to 7Li destroying the cells they are in. The dominant clinical agent is 4‐borono‐l‐phenylalanine, and this review comprehensively analyzes all of its reported patent and literature syntheses to help ...
Sarfraz Ahmad, Ming Pan, John J. Hayward, Massimo Sementilli, Lisa A. Porter, John F. Trant   +5 more
wiley   +1 more source

Advances and prospects of cell-penetrating peptides in tumor immunotherapy. [PDF]

Sci Rep
Yang D, Liu B, Sha H.
europepmc   +1 more source

Open‐Chain Tetrapyrroles Meet Metal Ions in the Functional Molecular Material Science

ChemPlusChem, EarlyView.
Open‐chain tetrapyrroles, synthesized via oxidative cleavage and condensation, offer greater structural flexibility than cyclic counterparts like porphyrins. Their tunable electronic and geometric properties through metalation enable applications in bioimaging, therapies, ion sensing, chiroptical materials, and spintronic devices, making them valuable ...
Aninda Ghosh, Sandipa Bhandari, Hiroyuki Furuta, Masatoshi Ishida   +3 more
wiley   +1 more source

γδT cells, a key subset of T cell for cancer immunotherapy. [PDF]

Front Immunol
Lv J, Liu Z, Ren X, Song S, Zhang Y, Wang Y.   +5 more
europepmc   +1 more source

Oncology Dose Optimization: Tailored Approaches to Different Molecular Classes

Clinical Pharmacology &Therapeutics, EarlyView.
Oncology dose optimization during the era of chemotherapy focused on identifying the maximum tolerated dose (MTD) for registrational trials, often resulting in significant toxicity. The advent of molecular targeted drugs and immunotherapies offers the potential to achieve similar efficacy with lower doses and fewer side effects, as maximal efficacy is ...
Jiawen Zhu, Amy Schroeder, Sabine Frank, Christophe Boetsch, Candice Jamois, Nastya Kassir, Koorosh Korfi, Elizabeth Punnoose, Anjali Vaze, Peter Trask, Pritti Gosai, Jane Fridlyand, Chunze Li   +12 more
wiley   +1 more source

Cancer immunotherapy in progress-an overview of the past 130 years. [PDF]

Int Immunol
Ikeda H.
europepmc   +1 more source

Expanding the Horizons of Phototherapy: A Review on the Superior Performance of Chalcogen‐Based Photosensitizers and Photothermal Agents for Cancer Therapy

ChemPhotoChem, EarlyView.
This review summarizes recent progress in chalcogen (S, Se, Te)‐incorporated photosensitizers and photothermal agent design. It explores synthetic strategies, spectroscopic and computational characterization, and in vitro/in vivo evaluations, showcasing the potential of these compounds for photodynamic and photothermal therapies.
Subhrakant Jena, Pranay Mohanty, Laxmipriya Dash, Himansu S. Biswal   +3 more
wiley   +1 more source

Editorial: Graft-versus leukemia (GVL) effect - immunobiology and ways to augment it. [PDF]

Front Immunol
Gooptu M.
europepmc   +1 more source

Standardization of Suspension and Imaging Mass Cytometry Single‐Cell Readouts for Clinical Decision Making

Cytometry Part A, EarlyView.
ABSTRACT Suspension and imaging mass cytometry are single‐cell, proteomic‐based methods used to characterize tissue composition and structure. Data assessing the consistency of these methods over an extended period of time are still sparse and are needed if mass cytometry‐based methods are to be used clinically.
Ruben Casanova, Shuhan Xu, Pierre Bost, Sujana Sivapatham, Andrea Jacobs, Stefanie Engler, Tumor Profiler Consortium, Rudolf Aebersold, Melike Ak, Faisal S Al‐Quaddoomi, I Albert Silvana, Jonas Albinus, Ilaria Alborelli, Sonali Andani, Per‐Olof Attinger, Marina Bacac, Daniel Baumhoer, Beatrice Beck‐Schimmer, Niko Beerenwinkel, Christian Beisel, Lara Bernasconi, Anne Bertolini, Bernd Bodenmiller, Ximena Bonilla, Lars Bosshard, Byron Calgua, Ruben Casanova, Stéphane Chevrier, Natalia Chicherova, Ricardo Coelho, Maya D’Costa, Esther Danenberg, Natalie R Davidson, Monica‐Andreea Drăgan, Reinhard Dummer, Stefanie Engler, Martin Erkens, Katja Eschbach, Cinzia Esposito, André Fedier, Pedro F Ferreira, Joanna Ficek‐Pascual, Anja L Frei, Bruno Frey, Sandra Goetze, Linda Grob, Gabriele Gut, Detlef Günther, Pirmin Haeuptle, Viola Heinzelmann‐Schwarz, Sylvia Herter, Rene Holtackers, Tamara Huesser, Alexander Immer, Anja Irmisch, Francis Jacob, Andrea Jacobs, Tim M Jaeger, Katharina Jahn, Alva R James, Philip M Jermann, André Kahles, Abdullah Kahraman, Viktor H Koelzer, Werner Kuebler, Jack Kuipers, Christian P Kunze, Christian Kurzeder, Kjong‐Van Lehmann, Mitchell Levesque, Ulrike Lischetti, Flavio C Lombardo, Sebastian Lugert, Gerd Maass, Markus G Manz, Philipp Markolin, Martin Mehnert, Julien Mena, Julian M Metzler, Nicola Miglino, Emanuela S Milani, Holger Moch, Simone Muenst, Riccardo Murri, Charlotte KY Ng, Stefan Nicolet, Marta Nowak, Monica Nunez Lopez, Patrick GA Pedrioli, Lucas Pelkmans, Salvatore Piscuoglio, Michael Prummer, Laurie Prélot, Natalie Rimmer, Mathilde Ritter, Christian Rommel, María L Rosano‐González, Gunnar Rätsch, Natascha Santacroce, Jacobo Sarabia del Castillo, Ramona Schlenker, Petra C Schwalie, Severin Schwan, Tobias Schär, Gabriela Senti, Wenguang Shao, Franziska Singer, Sujana Sivapatham, Berend Snijder, Bettina Sobottka, Vipin T Sreedharan, Stefan Stark, Daniel J Stekhoven, Tanmay Tanna, Alexandre PA Theocharides, Tinu M Thomas, Markus Tolnay, Vinko Tosevski, Nora C Toussaint, Mustafa A Tuncel, Marina Tusup, Audrey Van Drogen, Marcus Vetter, Tatjana Vlajnic, Sandra Weber, Walter P Weber, Rebekka Wegmann, Michael Weller, Fabian Wendt, Norbert Wey, Andreas Wicki, Mattheus HE Wildschut, Bernd Wollscheid, Shuqing Yu, Johanna Ziegler, Marc Zimmermann, Martin Zoche, Gregor Zuend, Mitchell P. Levesque, Reinhard Dummer, Bernd Bodenmiller, Stéphane Chevrier   +141 more
wiley   +1 more source

Evidence-Based Recommendations on the Use of Immunotherapies and Monoclonal Antibodies in the Treatment of Male Reproductive Cancers. [PDF]

Curr Oncol
Khalid F, Bodla ZH, Gaddameedi SR, Macasaet R, Yagnik K, Niaz Z, Fish PN, Du D, Shah S.   +8 more
europepmc   +1 more source