Results 21 to 30 of about 68,183 (284)

Adoptive immunotherapy in postoperative hepatocellular carcinoma: a systemic review.

open access: yesPLoS ONE, 2012
PurposeThe effectiveness of immunotherapy for postoperative hepatocellular carcinoma patients is still controversial. To address this issue, we did a systemic review of the literatures and analyzed the data with emphasis on the recurrence and survival ...
Feng Xie   +8 more
doaj   +1 more source

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma [PDF]

open access: yes, 2016
Immunotherapy approaches for pancreatic ductal adenocarcinoma (PDAC) have met with limited success. It has been postulated that a low mutation load may lead to a paucity of T cells within the tumor microenvironment (TME).
Alvarez, Hector A.   +13 more
core   +1 more source

Antigen-Specific Polyclonal Cytotoxic T Lymphocytes Induced by Fusions of Dendritic Cells and Tumor Cells [PDF]

open access: yes, 2010
The aim of cancer vaccines is induction of tumor-specific cytotoxic T lymphocytes (CTLs) that can reduce the tumor mass. Dendritic cells (DCs) are potent antigen-presenting cells and play a central role in the initiation and regulation of primary immune ...
Gong, Jianlin   +6 more
core   +11 more sources

Adoptive immunotherapy with interleukin-2 and lymphokine-activated killers in patients with malignant neoplasms of the female reproductive system (a review of literature)

open access: yesОпухоли женской репродуктивной системы, 2015
The review highlights current approaches to adoptive immunotherapy in patients with malignant neoplasms of the female reproductive system.In spite of the obvious advances made by scientists of the world in treating malignant neoplasms, the existing ...
A. N. Gritsai   +3 more
doaj   +1 more source

Adoptive Immunotherapy in Postoperative Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis.

open access: yesPLoS ONE, 2016
BackgroundAdoptive immunotherapy (AI) has been applied in the treatment of non-small-cell lung cancer (NSCLC) patients, but the value of postoperative AI has been inconclusive largely as a result of the small number of patients included in each study. We
Yuan Zeng   +7 more
doaj   +1 more source

TCR Gene Therapy: Challenges, Opportunities, and Future Directions

open access: yesCells, 2020
Adoptive immunotherapy with gene-engineered T cells has provided new treatment options for cancer patients [...]
Hans J. Stauss, Maxine G. B. Tran
doaj   +1 more source

Tumor-reactive immune cells protect against metastatic tumor and induce immunoediting of indolent but not quiescent tumor cells [PDF]

open access: yes, 2016
Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppressor cells and poor immunogenicity of the tumor-expressing self-antigens.
Bear, Harry D.   +8 more
core   +2 more sources

Adoptive immunotherapy for cytomegalovirus infection

open access: yesJournal of Applied Sciences and Environmental Management, 2005
We reported a case with interstitial pneumonia associated with cytomegalovirus (CMV) infection in whom clinical improvement was observed after the treatment with primary adoptive immunotherapy.
M D Kei Numazaki
doaj   +1 more source

Adoptive Natural Killer Cell Immunotherapy for Canine Osteosarcoma

open access: yesFrontiers in Veterinary Science, 2021
Osteosarcoma is the most common primary bone tumor in both humans and dogs. It is a highly metastatic cancer and therapy has not improved significantly since the inclusion of adjuvant chemotherapy into disease treatment strategies.
William C. Kisseberth, Dean A. Lee
doaj   +1 more source

Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer. [PDF]

open access: yes, 2017
INTRODUCTION: Colorectal cancer remains the second leading cause of cancer death in the United States, and new strategies to prevent, detect, and treat the disease are needed.
Aka, Allison A.   +5 more
core   +2 more sources

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