Results 71 to 80 of about 944,744 (294)

Ferroptosis in cancer and cancer immunotherapy

open access: yesCancer Communications, 2022
The hallmark of tumorigenesis is the successful circumvention of cell death regulation for achieving unlimited replication and immortality. Ferroptosis is a newly identified type of cell death dependent on lipid peroxidation which differs from classical ...
Lei Zhao   +9 more
semanticscholar   +1 more source

Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients [PDF]

open access: yes, 2013
Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients
Klingebiel, Thomas   +3 more
core   +2 more sources

Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response

open access: yesSignal Transduction and Targeted Therapy, 2022
Cancers are highly complex diseases that are characterized by not only the overgrowth of malignant cells but also an altered immune response. The inhibition and reprogramming of the immune system play critical roles in tumor initiation and progression ...
Dongrui Wang, Xian Wu, Yingchaun Sun
semanticscholar   +1 more source

Efficacy and safety of anticancer drug combinations: a meta-analysis of randomized trials with a focus on immunotherapeutics and gene-targeted compounds. [PDF]

open access: yes, 2020
Hundreds of trials are being conducted to evaluate combination of newer targeted drugs as well as immunotherapy. Our aim was to compare efficacy and safety of combination versus single non-cytotoxic anticancer agents. We searched PubMed (01/01/2001 to 03/
Barkauskas, Donald A   +4 more
core   +1 more source

Asymptomatic herpes simplex virus brain infection elicits cellular senescence phenotypes in the central nervous system of mice suffering multiple sclerosis-like disease

open access: yesCommunications Biology
Experimental autoimmune encephalomyelitis (EAE) is a demyelinating disease affecting the central nervous system (CNS) in animals that parallels several clinical and molecular traits of multiple sclerosis in humans.
Luisa F. Duarte   +13 more
doaj   +1 more source

The Role of Palliative Surgery for Malignant Bowel Obstruction and Perforation in Advanced Microsatellite Instability-High Colorectal Carcinoma in the Era of Immunotherapy: Case Report. [PDF]

open access: yes, 2020
The role of palliative surgery in the management of acute complications in patients with disseminated malignancy remains controversial given the complexity of assessing acute surgical risk and long-term oncologic outcome. With the emergence of checkpoint
Bold, Richard J   +13 more
core  

Immunotherapy of melanoma

open access: yesEuropean Journal of Cancer Supplements, 2013
Melanoma is considered one of the immunogenic - if not the most immunogenic - malignancies. This is based on several observations.1.Spontaneous remissions occur occasionally.2.In about 5% of melanomas no primary tumour is found. The genetic aberrations of these tumours closely resemble those of cutaneous melanomas, and therefore are suggestive of ...
openaire   +3 more sources

Autonomic modulation of the immune response and implications for CNS malignancies

open access: yesnpj Precision Oncology
While the central nervous system (CNS) has long been known to regulate global physiologic processes, its role in regulating immune responses has only relatively recently been appreciated.
Lucas P. Wachsmuth   +5 more
doaj   +1 more source

Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

open access: yesScience, 2020
New fecal microbiota for cancer patients The composition of the gut microbiome influences the response of cancer patients to immunotherapies. Baruch et al. and Davar et al.
E. Baruch   +31 more
semanticscholar   +1 more source

Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy

open access: yesTheranostics, 2022
Cancer immunotherapy has made tremendous clinical progress in advanced-stage malignancies. However, patients with various tumors exhibit a low response rate to immunotherapy because of a powerful immunosuppressive tumor microenvironment (TME) and ...
Bin Ji, Minjie Wei, Bin Yang
semanticscholar   +1 more source

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