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Taming Bacterial Toxins into an Anticancer Platform. [PDF]

open access: yesBiochem Biophys Res Commun
Yang C, Chen C.
europepmc   +1 more source

Recent Advances in Management of Vitiligo.

open access: yesIndian J Dermatol
Das K, Sarkar R, Sinha S.
europepmc   +1 more source
Some of the next articles are maybe not open access.

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CLL immunotoxins

Leukemia Research, 2005
Immunotoxins composed of cell-selective ligands covalently linked to peptide toxins have been developed for the treatment of chemotherapy relapsed or refractory malignancies including chronic lymphocytic leukemia (CLL). A number of CLL immunotoxins have been clinically tested including T101-ricin A, H65-ricin A, DAB(486)IL2, DAB(389)IL2, RFB4 (dsFv ...
Arthur E, Frankel, Robert J, Kreitman
openaire   +2 more sources

Recombinant immunotoxins

Breast Cancer Research and Treatment, 1996
Pseudomonas exotoxin has been genetically modified so that it targets cancer cells. This was accomplished by deleting its cell binding domain and replacing it with Fv fragments of antibodies that react with breast, colon, and other cancers. Several recombinant immunotoxins are now in clinical trials.
I, Pastan   +3 more
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Immunotoxins

Expert Opinion on Pharmacotherapy, 2000
Immunotoxins are molecules which contain a protein toxin connected to a targeting antibody. The goal of therapy is for the molecule to bind selectively to cancer cells, or to cells mediating autoimmune disease, internalise and then for the toxin to kill the cell.
openaire   +2 more sources

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