Results 131 to 140 of about 13,192,083 (308)

Impact Analysis of Wall-Caisson Composite Structure Construction Adjacent to Rail Transit Bridge

open access: yesChengshi guidao jiaotong yanjiu
[Objective] The construction deformation control adjacent to operational railways is of utmost importance in current rail transit planning and construction. Therefore, it is necessary to study the effect of the diaphragm wall-caisson composite structure (
CHEN Wei   +6 more
doaj   +1 more source

Farm-Level Impact Analysis of the Adoption of the Package of Technologies Introduced Under the Soybean Yield Gap Analysis Project (SYGAP) [PDF]

open access: yes, 1994
IndonesianStudi ini menganalisis dampak adopsi teknologi SYGAP di tingkat petani di Karawang dan Jombang. Umumnya hasil kedelai potensial tidak tercapai oleh petani peserta SYGAP di Karawang dan Jombang.
Sayaka, B. (Bambang)
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Reply to Comment on ‘Extreme weather events in early summer 2018 connected by a recurrent hemispheric wave-7 pattern’

open access: yesEnvironmental Research Letters
Circumglobal teleconnections from wave-like patterns in the mid-latitude jets can lead to synchronized weather extremes in the mid-latitudes of Northern and Southern hemispheres.
Kai Kornhuber   +4 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Citation Analysis Impact

open access: yesInternational Journal For Multidisciplinary Research
Impact of Citation Analysis on Research Fields.
openaire   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Warrnambool exchange fire: consumer and social impact analysis [PDF]

open access: yes
How can governments, communities, businesses and individuals prepare for a total communications blackout in the 21st century? Overview This report presents the findings of a research project which assessed the social impact of the Warrnambool exchange ...
Kaye Scholfield, Mark Gregory
core  

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