Results 151 to 160 of about 37,251,550 (358)
Budget impact analysis of two immunotherapy products for treatment of grass pollen-induced allergic rhinoconjunctivitis [PDF]
, 2012 Steen M Rønborg,1 Ulrik G Svendsen,2 Jesper S Micheelsen,3 Lars Ytte,4 Jakob N Andreasen,5 Lars Ehlers61The Pulmonology and Allergy Clinic of Copenhagen, Copenhagen, 2Bispebjerg Hospital, Copenhagen, 3Private ENT practice, Aalborg, 4General ...
Ytte L +5 more
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Global ChallengesThe concept of sustainability has been shaped by the history of environmental problems and ecological crises, and the scientific value of studying the past has long been recognized.
Georg Feulner
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The impact of Marmara earthquakes on regional economic development: a Difference in Differences analysis using nightlights [PDF]
This study provides empirical evidence on the impact of 1999 Marmara earthquakes on regional economic development. It employs nighttime light data as a proxy for economy activity which is an innovative tool to tackle with the limitations of traditional ...
Avşar, Alper
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Online activism and social media usage among Indonesian extremists [PDF]
, 2015 Indonesian extremists have a long history of online activism, but links to the Islamic State (still better known in Indonesia by its former acronym ISIS) have raised questions about whether social media usage is significantly changing patterns of ...
Institute for Policy Analysis of Conflict
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
The President’s intelligence community: relationship impact evaluation [PDF]
, 2017 Defense Analysis PosterBackground, Question, Argument: How does the relationship between the president and IC impact the chance of an intelligence failure occurring? What impact does a failure or success have on the relationship between the president and
Holtmeyer, Dane
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Fund for Shared Insight: Media Analysis [PDF]
, 2015 Fund for Shared Insight ("Shared Insight") is a collaborative effort among fundersthat pools financial and other resources to make grants to improve philanthropy.
ORS Impact
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