Results 51 to 60 of about 295,654 (265)

Impact phenomena in multiphase flows

, 2023
We want to be able to simulate and predict the loads generated during liquid-solid collisions, including the case when the liquid phase contains bubbles. Additionally, we simulate the passage of microparticles in a microchannel and study the way the particles clog either permanently or intermittently.
openaire   +1 more source

Impacts on Ocean Worlds Are Sufficiently Frequent and Energetic to Be of Astrobiological Importance

The Planetary Science Journal
Evidence for the beneficial role of impacts in the creation of urable or habitable environments on Earth prompts the question of whether meteorite impacts could play a similar role at other potentially urable/habitable worlds like Enceladus, Europa, and ...
Shannon M. MacKenzie, Alexandra Pontefract, R. Terik Daly, Jacob J. Buffo, Gordon R. Osinski, Christopher J. Cline II, Mark J. Cintala, Kathleen L. Craft, Mallory J. Kinczyk, Joshua Hedgepeth, Sarah M. Hörst, Abel Méndez, Ben K. D. Pearce, Angela M. Stickle, Steven D. Vance   +14 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Large Impacts onto the Early Earth: Planetary Sterilization and Iron Delivery

The Planetary Science Journal, 2022
Late accretion onto the Hadean Earth included large impacts that could have influenced early habitability, either by sterilizing the planet or alternatively catalyzing the origin of life by delivering iron required to create a reducing environment ...
Robert I. Citron, Sarah T. Stewart
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Delivery of DART Impact Ejecta to Mars and Earth: Opportunity for Meteor Observations

The Planetary Science Journal
NASA’s Double Asteroid Redirection Test (DART) and ESA’s Hera missions offer a unique opportunity to investigate the delivery of impact ejecta to other celestial bodies. We performed ejecta dynamical simulations using 3 million particles categorized into
Eloy Peña-Asensio, Michael Küppers, Josep M. Trigo-Rodríguez, Albert Rimola   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimorphos’s Material Properties and Estimates of Crater Size from the DART Impact

The Planetary Science Journal
On 2022 September 26, the Double Asteroid Redirection Test (DART) spacecraft intentionally collided with Dimorphos, the moon of the binary asteroid system 65803 Didymos.
Angela M. Stickle, Kathryn M. Kumamoto, Dawn M. Graninger, Mallory E. DeCoster, Wendy K. Caldwell, Jason M. Pearl, J. Michael Owen, Olivier Barnouin, Gareth S. Collins, R. Terik Daly, Isabel Herreros, Jens Ormö, Jessica Sunshine, Carolyn M. Ernst, Toshi Hirabayashi, Simone Marchi, Laura Parro, Harrison Agrusa, Megan Bruck Syal, Nancy L. Chabot, Andy F. Cheng, Thomas M. Davison, Elisabetta Dotto, Eugene G. Fahenstock, Fabio Ferrari, Martin Jutzi, Alice Lucchetti, Robert Luther, Nilanjan Mitra, Maurizio Pajola, Sabina Raducan, KT Ramesh, Andrew S. Rivkin, Alessandro Rossi, Paul Sánchez, Stephen R. Schwartz, Stefania Soldini, Jordan K. Steckloff, Filippo Tusberti, Kai Wünnemann, Yun Zhang   +40 more
doaj   +1 more source