Results 71 to 80 of about 295,654 (265)
Determinants of change in the duration of ice phenomena on the Vistula River in Toruń
Journal of Hydrology and Hydromechanics, 2015 Winter season temperatures are becoming warmer. However, the transformation of the ice regime on the Vistula River in Toruń has also been affected by river engineering.
Pawłowski Bogusław
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Earth-based observations of impact phenomena [PDF]
International Astronomical Union Colloquium, 1996 Earth-based observations at near- and mid-infrared wavelengths were obtained for at least 15 of the SL9 impacts, ranging from the spectacular G, K and L events to the barely-detected N and V impacts. Although there were a few exceptions, most of the IR lightcurves fit a common pattern of one or two relatively faint precursor flashes, followed several ...
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The impact of particle polydispersity on fluidization phenomena [PDF]
, 2020 Doctor of Philosophy (SCBE)
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Hydrous Chondrites under Shock
The Astrophysical JournalWe examine the shock response of a chondrule-like multicomponent silicate melt enriched with 2 wt% H _2 O, representative of hydrous chondrites, using ab initio molecular dynamics.
Adrien Saurety, Razvan Caracas
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The Planetary Science JournalImpact ejecta with velocities exceeding the escape velocity of planetary bodies become meteorites and dust particles in interplanetary space. We present a new method that allows simultaneous measurement of the size and velocity of the largest high ...
Akiko M. Nakamura +2 more
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FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source