Results 31 to 40 of about 1,880,493 (302)

Comparison of characteristics of women with normal glucose tolerance, impaired glucose tolerance and diabetes.

, 2019
Comparison of characteristics of women with normal glucose tolerance, impaired glucose tolerance and diabetes.
Amel Fayed (2552173), Samia Esmaeil (2552167), Hanadi Bakhsh (6180566), Ali M. Al-Hazmi (6180569), Safaa M. S. Tunkar (6180563), Hayfaa Wahabi (2552155), Amna R. Siddiqui (341167)   +6 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Carbohydrate Metabolism Disorders in Patients with Chronic Pancreatitis

Mìžnarodnij Endokrinologìčnij Žurnal, 2014
This article deals with dependence of the carbohydrate metabolism disorders on the duration of disease in patients with non-destructive chronic pancreatitis.
S.I. Ismailov, F.G. Nazyrov, B.A. Azizov
doaj   +1 more source

Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance: Rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial

, 2008
Patients with impaired glucose tolerance (IGT) have increased risk for developing type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Lifestyle modification and medication can prevent or delay progression to diabetes (PD), but whether such ...
Haffner, SM, Boolell, M, Duggal, A, NAVIGATOR,, McMurray, JJ, Bethel, MA, Study Group,, Holman, RR, McMurray, J, Califf, RM, Diem, Peter, Study Group   +11 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Associations of TG/HDL Ratio with the Risk of Prediabetes and Diabetes in Chinese Adults: A Chinese Population Cohort Study Based on Open Data

International Journal of Endocrinology, 2021
Background. In the global chronic diseases, type 2 diabetes shows a significant upward trend, and there are more people before prediabetes (impaired glucose tolerance).
Rongpeng Gong, Yuanyuan Liu, Gang Luo, Wenjing Liu, Ziqi Jin, Zixin Xu, Zheng Li, Lixin Yang, Xiaoxing Wei   +8 more
doaj   +1 more source

STUDY OF SERUM ADIPONECTIN LEVEL IN IMPAIRED GLUCOSE TOLERANCE SUBJECTS.

, 2019
The aim of study was to measure serum level of adiponectin in impaired glucose tolerance subjects and compare with healthy control subjects. In this study 120 Impaired Glucose Tolerance and 120 healthy subjects (age and gender matched) were enrolled ...
G.G. Kaushik., Poonam Yadav
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The Role of HbA1c and Oral Glucose Tolerance Test in the Diagnosis and Differentiation of Prediabetes: Article Review

Babcock University Medical Journal
Background: Prediabetes is a condition resulted when the level of glucose is between the normal and hyperglycaemic limits, and it is very important to follow up because it may be developed to diabetes mellitus It is critical to identify its 2 main ...
Mohammed Khalil, Sara Mutashar, Wassan Hussain   +2 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source