Results 31 to 40 of about 1,600 (181)

Anticoagulant action of low, physiologic, and high albumin levels in whole blood. [PDF]

PLoS ONE, 2017
Albumin is the most abundant plasma protein. Critical illness is often associated with altered, predominately decreased, serum albumin levels. This hypoalbuminaemia is usually corrected by administration of exogenous albumin.
Margret Paar, Christine Rossmann, Christoph Nusshold, Thomas Wagner, Axel Schlagenhauf, Bettina Leschnik, Karl Oettl, Martin Koestenberger, Gerhard Cvirn, Seth Hallström   +9 more
doaj   +1 more source

Effects of Spectral Interfering Substances on Light Transmission Platelet Aggregation Using Infrared Based Aggregometer. [PDF]

J Clin Lab Anal
This study aims to investigate the nature and extent of hemolyzed, icteric, or lipemic (HIL) interference on platelet aggregation using the TA‐8 V aggregometer (Diagnostica Stago, Asnières sur Seine) equipped with a near‐infrared light source outside the typical absorbance range of HIL.
Ibrahim-Kosta M, Zirka G, Carriere K, Ohlmann P, Alessi MC.   +4 more
europepmc   +2 more sources

Reduced platelet function in preterm neonates compared with term neonates

Research and Practice in Thrombosis and Haemostasis, 2022
Background A reduced platelet function might contribute to the longer bleeding time seen in preterm neonates. However, the previously used platelet function testing in neonates is limited due to methodological limitations, mainly caused by difficulties ...
Nadia Thrane Hovgesen, Claus V. B. Hviid, Alexander K. Grevsen, Anne Kirkeby Hansen, Anne‐Mette Hvas   +4 more
doaj   +1 more source

The Antiplatelet Action of S-Nitroso Human Serum Albumin in Whole Blood

Biomedicines, 2022
Nitric oxide donors (NO-donors) have been shown to have therapeutic potential (e.g., ischemia/reperfusion injury). However, due to their release rate/antiplatelet properties, they may cause bleeding in patients.
Melina Tsiountsioura, Gerhard Cvirn, Axel Schlagenhauf, Harald Haidl, Kathrin Zischmeier, Nicole Janschitz, Martin Koestenberger, Willibald Wonisch, Margret Paar, Thomas Wagner, Eva-Christine Weiss, Seth Hallström   +11 more
doaj   +1 more source

Evaluation of platelet function in essential thrombocythemia under different analytical conditions

Platelets, 2020
Background. Studies of platelet aggregation (PA) in essential thrombocythemia (ET) reported contrasting results, likely due to differences in analytical conditions. Objective. We investigated platelet aggregation using different techniques and analytical
Federico Lussana, Eti Alessandra Femia, Mariateresa Pugliano, Gianmarco Podda, Cristina Razzari, Norma Maugeri, Anna Lecchi, Sabrina Caberlon, Giancarla Gerli, Marco Cattaneo   +9 more
doaj   +1 more source

Platelet aggregation function test for children in order to determine the normative values in different age groups

Лечащий Врач, 2022
Mucocutaneous bleeding and thrombocytopenia are commonly encountered in pediatric patients. It is important for pediatricians to recognize when these signs and symptoms warrant further investigation and subsequently what investigations are most helpful ...
O. B. Gordeeva, M. S. Karaseva, M. A. Babaikina, N. D. Vashakmadze, M. A. Soloshenko, O. Ya. Smirnova, D. S. Ovchinnikov   +6 more
doaj   +1 more source

The impact of pneumatic tube transport on whole blood coagulation and platelet function assays

Platelets, 2018
Pneumatic tube is an attractive way to transport blood samples from the emergency department to the central laboratory facility. We aimed to investigate the impact of pneumatic tube transportation on blood samples for analysis of whole blood coagulation ...
Peter H. Nissen, Dorte E. Wulff, Niels Tørring, Anne-Mette Hvas   +3 more
doaj   +1 more source

Inhibition of agonist-induced platelet aggregation by magnesium sulfate warrants its use as an alternative in vitro anticoagulant in pseudothrombocytopenia

Platelets, 2020
MgSO4 is effective in preventing spontaneous in vitro platelet agglutination in anticoagulant-induced pseudothrombocytopenia (PTCP). In order to learn more about its potential as an in vitro anticoagulant, platelets from MgSO4-anticoagulated blood were ...
Steffen Mannuß, Peter Schuff-Werner, Katrin Dreißiger, Christine Burstein   +3 more
doaj   +1 more source

Evaluation of platelet function in thrombocytopenia

Platelets, 2018
Whole blood aggregometry is a functional assay for determination of platelet function. Until now, whole blood aggregometry has not been considered feasible at low platelet counts.
Mette Tiedemann Skipper, Peter Rubak, Jesper Stentoft, Anne-Mette Hvas, Ole Halfdan Larsen   +4 more
doaj   +1 more source

Protamine stimulates platelet aggregation in vitro with activation of the fibrinogen receptor and alpha-granule release, but impairs secondary activation via ADP and thrombin receptors

Platelets, 2021
Heparin and protamine are fundamental in the management of anticoagulation during cardiac surgery. Excess protamine has been associated with increased bleeding.
Mattias Törnudd, Sofia Ramström, John-Peder Escobar Kvitting, Joakim Alfredsson, Richard Pihl, Sören Berg   +5 more
doaj   +1 more source