Results 61 to 70 of about 1,600 (181)
Experimental Biology and Medicine, 1985 Although the domestic swine is commonly employed for physiological studies of the coronary circulation, there is relatively little data available concerning the responsiveness in whole blood of normal porcine platelets to standard physiological agonists.
H, Gewirtz +3 more
openaire +2 more sources
Кардиоваскулярная терапия и профилактика, 2022 Aim. To study the tolerability, safety, pharmacokinetics (PK) and pharmacodynamics of single intravenous infusions of Angipur in healthy male volunteers.Material and methods. The Phase I trial included 20 healthy male volunteers (mean age, 30,8±7,7 years;
S. B. Fitilev +6 more
doaj +1 more source
Perioperative changes of response to antiplatelet medication in vascular surgery patients.
PLoS ONE, 2020 IntroductionReduced antiplatelet activity of aspirin (ALR) or clopidogrel (CLR) is associated with an increased risk of thromboembolic events. The reported prevalence data for low-responders vary widely and there have been few investigations in vascular ...
Thomas Hummel +6 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 4, Page 3152-3162, August 2025.The METAB‐HTX trial is a prospective cohort study, evaluating cardiac and systemic metabolism among heart transplant recipients. Myocardial function, energetic and metabolism, allograft vasculopathy, allograft rejection, glucometabolism, lipometabolism, liver‐ and kidney function, leucocyte signatures and thromboinflammation will be evaluated ...
Amin Polzin +21 more
wiley +1 more source
Platelet‐Activating Factor Promotes Neutrophil Activation and Platelet–Neutrophil Complex Formation
Scandinavian Journal of Immunology, Volume 102, Issue 2, August 2025.The present study analysed the effect of the proinflammatory mediator platelet‐activating factor (PAF) on neutrophils both in vitro and in an animal‐free ex vivo whole blood model, with a particular focus on the formation of platelet–neutrophil complexes (PNCs).
Lisa Wohlgemuth +15 more
wiley +1 more source
Egyptian Journal of Critical Care Medicine, 2018 Extracorporeal membrane oxygenation (ECMO) is an established therapy for patients with cardiac failure, pulmonary failure or cardiopulmonary failure. To suppress the activation of the coagulation cascade, anticoagulation is necessary.
Poonam Malhotra Kapoor +2 more
doaj +1 more source
Transfusion, Volume 65, Issue 6, Page 1072-1082, June 2025.Abstract Background Apheresis procedures and the infusion of acid‐citrate‐dextrose induce metabolic alterations that may influence glucose metabolism. Although insulin resistance (IR), overweight, and obesity are not exclusion criteria for blood donation, their impact during apheresis procedure and on post‐donation metabolic responses remains ...
Edgar Barrientos‐Galeana +14 more
wiley +1 more source
The role of evidence-based algorithms for rotational thromboelastometry-guided bleeding management [PDF]
Korean Journal of Anesthesiology, 2019 Rotational thromboelastometry (ROTEM) is a point-of-care viscoelastic method and enables to assess viscoelastic profiles of whole blood in various clinical settings.
Klaus Görlinger +6 more
doaj +1 more source
Haemophilia, Volume 31, Issue 3, Page 485-493, May 2025.ABSTRACT Introduction Heavy menstrual bleeding (HMB) is a common presenting symptom in women with bleeding disorders, yet haemostatic testing is sometimes overlooked, even when refractory HMB requires surgical intervention. Aim To determine the prevalence of bleeding disorders in women referred for surgical management of HMB and investigate screening ...
Alison Delaney +8 more
wiley +1 more source
Physiological Reports, Volume 13, Issue 9, May 2025.Abstract Nearly 40% of US adults over the age of 50 use aspirin (ASA) therapy for the primary or secondary prevention of cardiovascular disease. Systemic platelet cyclooxygenase inhibition with low‐dose ASA attenuates reflex cutaneous vasodilation and accelerates the rate of rise of core temperature during passive heating in middle‐aged adults.
Kat G. Fisher +4 more
wiley +1 more source