Results 121 to 130 of about 6,921,664 (320)

An Irregular Current Injection Islanding Detection Method Based on an Improved Impedance Measurement Scheme

open access: yesEnergies, 2018
One class of islanding detection methods, known as impedance measurement-based methods and voltage change monitoring-based methods, are implemented through injecting irregular currents into the network, for which reason they are defined in this paper as ...
Menghua Liu   +4 more
doaj   +1 more source

Reflection oscillators employing series resonant crystals' [PDF]

open access: yes, 1989
A reflection oscillator is provided which employs an active device operated in its roll-off region and two resonant circuits. For an oscillator employing a bipolar transistor, the emitter is connected to a series resonant capacitor-crystal network and ...
Kleinberg, Leonard L.
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Scattering Statistics in Nonlinear Wave Chaotic Systems

open access: yes, 2018
The Random Coupling Model (RCM) is a statistical approach for studying the scattering properties of linear wave chaotic systems in the semi-classical regime. Its success has been experimentally verified in various over-moded wave settings, including both
Anlage, Steven M.   +3 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Study on Low-Frequency Oscillation in Train-Traction Network Coupling System Based on Impedance Model

open access: yes机车电传动, 2017
The low-frequency oscillation phenomenon had been frequently occurred in China electrified railways, which caused the traction locked of the train and the protection tripped of power supply system as well as other accidents.
TAO Yan
doaj  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Accessibility of urban agglomeration integrated passenger transport network considering travel impedance

open access: yesJournal of Highway and Transportation Research and Development
To clarify the multi-layer spatial structure of urban agglomeration integrated passenger transport networks and enhance their functional attributes, a new model is proposed that considered urban transport transfer from a novel perspective of coupling ...
Chengbing Li, Peng Wu, Yunfei Li
doaj   +1 more source

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