Results 41 to 50 of about 99,909 (304)

Ambiguous Bodies, Biopower and the Ideologies of Science Fiction [PDF]

open access: yes, 2016
Contemporary Hollywood film narrates the fear of monstrous science; attending to the modulations of medicine, capital and the body. The filmic body is employed to illustrate the power of the new biotechnologies to create and sustain life and the new ...
Flynn, Susan
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Optimal number of imperfect repairs for deteriorating systems [PDF]

open access: yesInternational Journal of Industrial Engineering and Production Research
A periodic maintenance policy through either an imperfect repair or replacement is proposed for a repairable system. It is assumed that the system is subject to an inverse Gaussian degradation process.
Khatereh Rajinia, Mostafa Razmkhah
doaj  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Preventive maintenance strategy of electric multiple unit critical equipment based on replacement repair

open access: yes机车电传动, 2022
Considering that the entire electric multiple unit (EMU) needs to be withdrawn from service for carrying out preventive maintenance (PM) of the critical equipment, leading to an increase to downtime loss, the concept of replacement repair is proposed in ...
XIONG Lü, LIU Zhilong
doaj  

Estimation of component redundancy in optimal age maintenance [PDF]

open access: yes, 2012
The classical Optimal Age-Replacement defines the maintenance strategy based on the equipment failure consequences. For severe consequences an early equipment replacement is recommended. For minor consequences the repair after failure is proposed.
Garção, José   +2 more
core  

Models of Imperfect Repair

open access: yes, 2012
Repair is a type of maintenance carried out on an item after it fails. A failure may occur any time, hence the times to repair cannot be pre-specified. Methods used to model times to failures are normally stochastic processes such as the renewal process and the homogeneous Poisson process, depending on the effectiveness of a repair.
Luo, M., Wu, S., Scarf, P.
openaire   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Imperfect Preventive Maintenance Model Study Based On Reliability Limitation

open access: yesMATEC Web of Conferences, 2016
Effective maintenance is crucial for equipment performance in industry. Imperfect maintenance conform to actual failure process. Taking the dynamic preventive maintenance cost into account, the preventive maintenance model was constructed by using age ...
Zhou Qian, Sun Yufeng
doaj   +1 more source

A multi-objective framework for the optimisation of life-cycle costs of wind turbines [PDF]

open access: yes, 2016
Peer reviewedPublisher ...
Hanish Nithin, Anu, Omenzetter, Piotr
core  

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