Results 91 to 100 of about 15,148,604 (394)

A refined compilation of implementation strategies: results from the Expert Recommendations for Implementing Change (ERIC) project

open access: yesImplementation Science, 2015
BackgroundIdentifying, developing, and testing implementation strategies are important goals of implementation science. However, these efforts have been complicated by the use of inconsistent language and inadequate descriptions of implementation ...
B. Powell   +7 more
semanticscholar   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Image quality comparisons of coil setups in 3T MRI for brain and head and neck radiotherapy simulations

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose MRI is increasingly used for brain and head and neck radiotherapy treatment planning due to its superior soft tissue contrast. Flexible array coils can be arranged to encompass treatment immobilization devices, which do not fit in diagnostic head/neck coils. Selecting a flexible coil arrangement to replace a diagnostic coil should rely
Evangelia Kaza   +6 more
wiley   +1 more source

A Verified Implementation of B+-Trees in Isabelle/HOL [PDF]

open access: yesarXiv, 2022
In this paper we present the verification of an imperative implementation of the ubiquitous B+-tree data structure in the interactive theorem prover Isabelle/HOL. The implementation supports membership test, insertion and range queries with efficient binary search for intra-node navigation.
arxiv  

Vertical Implementation

open access: yesInformation and Computation, 2001
AbstractWe investigate criteria to relate specifications and implementations belonging to conceptually different levels of abstraction. For this purpose, we introduce the generic concept of a vertical implementation relation, which is a family of binary relations indexed by a refinement function that maps abstract actions onto concrete processes and ...
Roberto Gorrieri, Arend Rensink
openaire   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Joint application of hybrid iterative reconstruction and adaptive filters on neck‐and‐shoulder CT imaging: A clinical evaluation

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To assess whether the joint application of hybrid iterative reconstruction (HIR) and an adaptive filter (AF) could reduce streak artifacts and improve image quality of neck‐and‐shoulder computed tomography (CT). Methods This study included 96 patients with suspicious neck lesions who underwent a routine nonenhanced scan on a 64‐slice ...
Wenfeng Jin   +6 more
wiley   +1 more source

Clever Design, Unexpected Obstacles: Insights on Implementing a Quantum Boltzmann Machine [PDF]

open access: yesarXiv, 2023
We have implemented a gated-based quantum version of a restricted Boltzmann machine for approximating the ground state of a Pauli-decomposed qubit Hamiltonian. During the implementation and evaluation, we have noticed a variety of unexpected topics. It starts from limitations due to the structure of the algorithm itself and continues with constraints ...
arxiv  

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

Clinical commissioning of an adaptive radiotherapy platform: Results and recommendations

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Online adaptive radiotherapy platforms present a unique challenge for commissioning as guidance is lacking and specialized adaptive equipment, such as deformable phantoms, are rare. We designed a novel adaptive commissioning process consisting of end‐to‐end tests using standard clinical resources.
Kelly Kisling   +5 more
wiley   +1 more source

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