Results 91 to 100 of about 9,393,515 (292)

Multimodal Grammar Implementation [PDF]

, 2012
This paper reports on an implementation of a multimodal grammar of speech and co-speech gesture within the LKB/PET grammar engineering environment. The implementation extends the English Resource Grammar (ERG, Flickinger (2000)) with HPSG types and rules
Alahverdzhieva, Katya, Flickinger, Dan, Lascarides, Alex   +2 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Generalizing Boolean Satisfiability III: Implementation

, 2011
This is the third of three papers describing ZAP, a satisfiability engine that substantially generalizes existing tools while retaining the performance characteristics of modern high-performance solvers.
Dixon, H. E., Ginsberg, M. L., Hofer, D., Luks, E. M., Parkes, A. J.   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Determinants of implementation of continuous glucose monitoring for patients with Insulin-Treated type 2 diabetes: a national survey of primary care providers

BMC Primary Care
Objectives To identify determinants of continuous glucose monitoring (CGM) implementation from primary care providers’ (PCPs’) perspectives and examine the associations of these determinants with both PCP intent to discuss CGM with eligible patients and ...
Varsha G. Vimalananda, Ben Kragen, Alison J. Leibowitz, Shirley Qian, Jolie Wormwood, Amy M. Linsky, Patricia Underwood, Paul R. Conlin, Bo Kim   +8 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Use of the Internet to Counter the Appeal of Extremist Violence. Conference Summary & Follow-up/ Recommendations

Perspectives on Terrorism, 2012
by the United Nations Counterterrorism Implementation Task Force (CTITF), Working Group on Use of the Internet for Terrorist Purposes  Riyadh, 24 - 26 January 2011. 
(CTITF) United Nations Counterterrorism Implementation Task Force
doaj  

Secure implementation [PDF]

Theoretical Economics, 2004
Strategy-proofness, requiring that truth-telling be a dominant strategy, is a standard concept in social choice theory. However, this concept has serious drawbacks. In particular, many strategy-proof mechanisms have multiple Nash equilibria, some of which produce the wrong outcome. A possible solution to this problem is to require double implementation
Saijo, Tatsuyoshi, Sjostrom, Tomas, Yamato, Takehiko   +2 more
openaire   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Automated tests for diagnosing and monitoring cognitive impairment: a diagnostic accuracy review

Health Technology Assessment, 2016
Background: Cognitive impairment is a growing public health concern, and is one of the most distinctive characteristics of all dementias. The timely recognition of dementia syndromes can be beneficial, as some causes of dementia are treatable and are ...
Rabeea’h W Aslam, Vickie Bates, Yenal Dundar, Juliet Hounsome, Marty Richardson, Ashma Krishan, Rumona Dickson, Angela Boland, Eleanor Kotas, Joanne Fisher, Sudip Sikdar, Louise Robinson   +11 more
doaj   +1 more source