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DELE1 tracks perturbed protein import and processing in human mitochondria [PDF]

open access: yesNature Communications, 2022
Human mitochondria experience substantial stress and malfunction in neurological diseases. Here, the authors reveal DELE1 as a multimodal sensor of protein import and processing defects, rationalizing mitochondrial stress integration.
Evelyn Fessler   +2 more
doaj   +3 more sources

Proteasomal degradation induced by DPP9‐mediated processing competes with mitochondrial protein import

open access: yesEMBO Journal, 2020
Plasticity of the proteome is critical to adapt to varying conditions. Control of mitochondrial protein import contributes to this plasticity. Here, we identified a pathway that regulates mitochondrial protein import by regulated N‐terminal processing ...
Markus Habich   +2 more
exaly   +3 more sources

Membrane Processing and Steady-State Regulation of the Alternative Peroxisomal Import Receptor Pex9p

open access: yesFrontiers in Cell and Developmental Biology, 2020
Import of peroxisomal matrix proteins with a type 1 peroxisomal targeting signal (PTS1) in Saccharomyces cerevisiae is facilitated by cytosolic import receptors Pex5p and Pex9p. While Pex5p has a broad specificity for all PTS1 proteins independent of the
Markus Rudowitz   +2 more
doaj   +4 more sources

Import Processing and Trade Costs [PDF]

open access: yesSSRN Electronic Journal, 2021
We estimate import processing costs based on the time it takes to import. Our theory extends existing time-cost measures to account for uncertainty in import processing. We use detailed, highly disaggregated data on import processing dates and import values to provide evidence for our theory and estimate processing costs consistent with the theory. The
Jerónimo Carballo   +3 more
core   +8 more sources

METHOD OF OPEN DATA IMPORT AND PROCESSING IN LBS-PLATFORM [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2016
The paper proposes solution for the problem of Open Data integration and geocontext markup in LBS-platform. Solution method is based on providing unified platform-level interfaces for executing modular and reusable Open Data import instruments.
M. M. Zaslavskiy, S. I. Balandin
doaj   +2 more sources

Evidence for a link between translocation and processing during protein import into soybean mitochondria

open access: yesBiochimica Et Biophysica Acta - Molecular Cell Research, 1996
The effect of metal chelators on protein import was investigated using isolated soybean mitochondria and soybean precursor proteins. Adding 1,10-phenanthroline, a metal chelator that can cross both mitochondrial membranes abolished import of both the ...
James Whelan, David A Day
exaly   +3 more sources

Role of the Mitochondrial Protein Import Machinery and Protein Processing in Heart Disease

open access: yesFrontiers in Cardiovascular Medicine, 2021
Mitochondria are essential organelles for cellular energy production, metabolic homeostasis, calcium homeostasis, cell proliferation, and apoptosis.
Ming-Hui Zou, Zou Ming-Hui
exaly   +2 more sources

Signals Required for the Import and Processing of the Alternative Oxidase into Mitochondria

open access: yesJournal of Biological Chemistry, 1999
The critical residues involved in targeting and processing of the soybean alternative oxidase to plant and animal mitochondria was investigated. Import of various site-directed mutants into soybean mitochondria indicated that positive residues throughout
Sara Sjöling   +2 more
exaly   +2 more sources

Relative Importance in Sentence Processing [PDF]

open access: yesProceedings of the 59th Annual Meeting of the Association for Computational Linguistics and the 11th International Joint Conference on Natural Language Processing (Volume 2: Short Papers), 2021
accepted at ACL ...
Hollenstein, Nora, Beinborn, Lisa
openaire   +5 more sources

Protein import into plant mitochondria: signals, machinery, processing, and regulation

open access: yesJournal of Experimental Botany, 2014
Monika W Murcha   +2 more
exaly   +2 more sources

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