Results 141 to 150 of about 21,607 (213)

Model for importin 7- and Nup358-assisted import of hTERT.

, 2014
Cytoplasmic hTERT (TERT) interacts with Nup358, the major component of the cytoplasmic filaments of the NPC (blue rods). Upon binding of importin 7, hTERT is translocated across the NPC.
Sarah Wälde (525477), Ralph H. Kehlenbach (346825), Annegret Nath (525478), Cornelia Frohnert (525475), Saskia Hutten (525476)   +4 more
core   +1 more source

Sphingosine simultaneously inhibits nuclear import and activates PP2A by binding importins and PPP2R1A

The EMBO Journal
Sphingosine and constrained analogs like FTY720 and SH-BC-893 restrain tumor growth through incompletely defined mechanisms that include protein phosphatase 2A (PP2A) activation.
Vaishali Jayashankar, Peter Kubiniok, Alison N McCracken, Rebeca G Gentry, Kazumi H Eckenstein, Lorenzo Sernissi, Vito Vece, Jean-Baptiste Garsi, Sarah Y Valles, Sunhee Jung, Natalie C Hoffman, Arielle S Perrochon, Elizabeth M Selwan, Brendan T Finicle, Mary Pitman, DaWei Lin, Éric Bonneil, Ruijuan Xu, Cungui Mao, Peter Kaiser, David A Fruman, David Mobley, Cholsoon Jang, Stephen Hanessian, Pierre Thibault, Aimee L Edinger   +25 more
doaj   +1 more source

Initial Characterization of two novel spindle proteins, CHICA and HURP [PDF]

, 2008
During mitotic spindle assembly, the sister chromatids have to be captured by kinetochore (K) -fibers (bundles of kinetochore microtubules; KMTs) to ensure stable attachment of the chromosomes.
Nagel, Susanna
core  

How is expression of the importin-β encoding Ketel gene of Drosophila regulated? [PDF]

, 2008
Villányi Zoltán
core  

Targeting Nuclear Import of Thyroid Hormone Receptor Alpha with Natural Polyphenols: Potential Mechanism for Lipolysis in Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

Curr Issues Mol Biol
Konstantinou EK, Panagiotopoulos AA, Dimitriou M, Castanas E.   +3 more
europepmc   +1 more source

Signaling into the nucleus through the importin 7 pathway. [PDF]

J Biol Chem
Palchevska O, Ko YH, Cingolani G.
europepmc   +1 more source

Nuclear-Cytoplasmic Axis in Cancer: From Protein Mislocalization to Anticancer Drug Resistance. [PDF]

Oncol Res
Zhu X, He M, Wang L, Su R, Zhong L, Guo T, Wang H, Zou D.   +7 more
europepmc   +1 more source

Structures of Nicotiana benthamiana importin-α1 complexes reveal mechanisms for plant virus NLS recognition. [PDF]

Plant J
Liu Y, Wang Z, Zhang Y, Wang X, Wei S, Yang M, Zhang Y, Li D, Qi X, Zhao X, Chen Z.   +10 more
europepmc   +1 more source

The N-terminal extension of ribosomal protein Rps2 shapes its early fate through Chaperone-Importin competition and arginine methylation. [PDF]

J Biol Chem
Mack M, Pillet B, Holton N, Zierler I, Himpich S, Jessen P, Wahl MC, Kressler D, Pertschy B.   +8 more
europepmc   +1 more source

Ivermectin Inhibits Stress Granule Clearance by Blocking the De Novo Synthesis of Hsp70 in Neuroblastoma Cells. [PDF]

Cells
Chu S, Anim EP, Salehi-Tabar R, White JH, Stochaj U.   +4 more
europepmc   +1 more source