Importin α plays a pivotal role in the classical nuclear protein import pathway. Importin α shuttles between nucleus and cytoplasm, binds nuclear localization signal-bearing proteins, and functions as an adapter to access the importin β-dependent import ...
Prehn, S. +10 more
core
NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4.
NF-kappaB transcription factors are retained in the cytoplasm in an inactive form until they are activated and rapidly imported into the nucleus. We identified importin alpha3 and importin alpha4 as the main importin alpha isoforms mediating TNF-alpha-stimulated NF-kappaB p50/p65 heterodimer translocation into the nucleus.
Riku, Fagerlund +4 more
openaire +1 more source
How is expression of the importin-β encoding Ketel gene of Drosophila regulated? [PDF]
Villányi Zoltán
core
Nuclear PD-L1: an emerging oncogenic driver and promising therapeutic target in cancer. [PDF]
Guo C +5 more
europepmc +1 more source
CDK9 interacts with a RanGTP-importin-β complex to regulate erythroid enucleation. [PDF]
Newton LM +7 more
europepmc +1 more source
Unveiling nuclear localization signals in human arginine deiminase proteins. [PDF]
Neira JL +3 more
europepmc +1 more source
Histone Nuclear Import and Beyond: Multifunctional Roles of Importins. [PDF]
Bernardes N, Chook YM.
europepmc +1 more source
Importin-9 recognizes the winged-helix fold of ETS transcription factors to mediate nuclear import. [PDF]
McConville M +7 more
europepmc +1 more source
Enolase 1 suppresses influenza A virus replication by blocking the nuclear import of the viral ribonucleoprotein complex. [PDF]
Kong X, Liu J, Zhu Q, Xu S.
europepmc +1 more source
The molecular mechanism underlying the differential subcellular distribution of dystrophin Dp71 isoforms. [PDF]
Alamillo-Iniesta A +13 more
europepmc +1 more source

