Results 11 to 20 of about 137,611 (281)

Evaluation of Next-Generation H3 Influenza Vaccines in Ferrets Pre-Immune to Historical H3N2 Viruses

open access: yesFrontiers in Immunology, 2021
Each person has a unique immune history to past influenza virus infections. Exposure to influenza viruses early in life establishes memory B cell populations that influence future immune responses to influenza vaccination.
James D. Allen, Ted M. Ross, Ted M. Ross
doaj   +1 more source

Differences in expression rather than methylation at placenta-specific imprinted loci is associated with intrauterine growth restriction

open access: yesClinical Epigenetics, 2019
Background Genome-wide studies have begun to link subtle variations in both allelic DNA methylation and parent-of-origin genetic effects with early development.
Ana Monteagudo-Sánchez   +14 more
doaj   +1 more source

Retrotransposon silencing by DNA methylation can drive mammalian genomic imprinting [PDF]

open access: yes, 2015
Among mammals, only eutherians and marsupials are viviparous and have genomic imprinting that leads to parent-of-origin-specific differential gene expression. We used comparative analysis to investigate the origin of genomic imprinting in mammals. PEG10 (
Alsop, Amber   +12 more
core   +1 more source

Retinoblastoma makes its mark on imprinting in plants [PDF]

open access: yes, 2008
Genomic imprinting results in the preferential expression of alleles from either the maternal or paternal chromosomes. This epigenetic process occurs in embryonic and extra-embryonic (placental) tissues of mammals, but only in the extra-embryonic ...
Liliana M Costa   +29 more
core   +2 more sources

Imprinting and its disorders in evolutionary perspective

open access: yesActa Medica Lituanica, 2014
Bacground. Genomic imprinting is one of the best-studied epigenetic phenomena involving all the main epigenetic processes. Recent investigations led to a huge expansion of knowledge in this field and changed some established paradigms regarding ...
Birutė Tumienė   +2 more
doaj   +1 more source

More Than Just a Barrier: The Immune Functions of the Airway Epithelium in Asthma Pathogenesis

open access: yesFrontiers in Immunology, 2020
Allergic bronchial asthma is a chronic disease of the airways that is characterized by symptoms like respiratory distress, chest tightness, wheezing, productive cough, and acute episodes of broncho-obstruction. This symptom-complex arises on the basis of
Andreas Frey   +11 more
doaj   +1 more source

The long non-coding RNA Kcnq1ot1 controls maternal p57 expression in muscle cells by promoting H3K27me3 accumulation to an intragenic MyoD-binding region [PDF]

open access: yes, 2019
BACKGROUND: The cell-cycle inhibitor p57kip2 plays a critical role in mammalian development by coordinating cell proliferation and differentiation in many cell types.
Andresini, Oriella   +5 more
core   +4 more sources

A global disorder of imprinting in the human female germ line [PDF]

open access: yes, 2002
Imprinted genes are expressed differently depending on whether they are carried by a chromosome of maternal or paternal origin. Correct imprinting is established by germline-specific modifications; failure of this process underlies several inherited ...
A Kerjean   +30 more
core   +1 more source

Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors

open access: yesNature Communications, 2017
Altered genomic imprinting is frequently reported in cancer. Here, the authors analyze copy number and methylation in cancer cell lines and primary tumors to show that imprinted methylation profiles represent the accumulation of copy number alteration ...
Alex Martin-Trujillo   +9 more
doaj   +1 more source

Neurophysiological Mechanisms of Cow–Calf Bonding in Buffalo and Other Farm Animals

open access: yesAnimals, 2021
In buffaloes and other mammalian farm species, the mother provides food and protection to the young, but she is also the main source of behavioral and social learning for the offspring.
Agustín Orihuela   +6 more
doaj   +1 more source

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